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Lower drug dose works just as well to prevent dangerous blood pressure drop in elderly surgery

NCT ID NCT07077265

Symptom relief Sponsor: Kasr El Aini Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a lower dose of the drug norepinephrine (0.07 mcg/kg/min) works as well as a higher dose (0.1 mcg/kg/min) to prevent dangerously low blood pressure in elderly patients (over 65) during hip surgery with spinal anesthesia. The trial included 84 patients and measured average blood pressure, as well as episodes of low blood pressure, high blood pressure, and slow heart rate. The goal is to find a safer, effective dose for this vulnerable group.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

84 people

The number who actually took part.

Started

Aug 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Elderly patients (\>65) * ASA I-II-III * scheduled for hip surgery under spinal anesthesia Exclusion Criteria: * Contraindication of spinal anesthesia * history of allergy to any of the study's drugs, * Patients with cardiac morbidities (impaired contractility with ejection fraction \< 50%, heart block, arrhythmias) * patients with uncontrolled hypertension

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Elderly (people aged 65 or more) Hypotension after spinal anesthesia Spinal aneshtesia

Contacts and locations

Locations

  • Kasr Alainy Hospital

    Cairo, 11562, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.