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Plasma zaps mouth ulcer pain away?

NCT ID NCT07322666

Symptom relief Sponsor: National Institute of Nuclear Research - Mexico Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested a new treatment called non-thermal plasma (NTP) for painful mouth ulcers in 50 adults. The goal was to see if NTP could speed up healing and reduce pain better than standard laser therapy or a placebo. Participants were randomly assigned to one of three groups and had their ulcer size, pain, and healing time measured.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Feb 2019

Finished

Feb 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 years of age * Patients of both sexes * Patients with recurrent oral ulcers (ROU) * Patients without oral soft tissue diseases * Patients with at least one recurrent ulcer Exclusion Criteria: * Patients under 18 years of age * Patients with ROU of more than 48 hours' duration * Patients with gingivitis and/or periodontitis * Patients undergoing maxillofacial orthopedic and/or orthodontic treatment * Patients with ill-fitting dentures

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Conditions

The condition(s) this trial relates to.

aphthous stomatitis canker sore Oral Ulcer Pain stomatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aphthous ulcer Stomatitis

Contacts and locations

Locations

  • Plasma Physics Laboratory, National Institute of Nuclear Research

    Ocoyoacac, State of Mexico, 52750, Mexico

More trials for these conditions

Other studies related to the condition(s) this trial covers.