Gum disease protein levels measured in small study
NCT ID NCT06400069
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study measured levels of a protein called NLRP6 in the blood of 50 adults with chronic periodontitis (long-term gum disease). Researchers wanted to see if NLRP6 levels are linked to gum health. The study is complete and aimed at understanding the disease better, not testing a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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50 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients referred to the periodontology department of the University School of Dentistry Medical sciences of Babol
- Ages
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25 to 79 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age: At least 25 years old * Clinical diagnosis of chronic periodontitis * At least 15 teeth in the mouth Exclusion Criteria: * premalignant lesions and cancer of the oral cavity * periodontal treatment in the last 6 months * systemic disorders affecting the periodontal condition (autoimmunity and endocrine disorders) * diabetes mellitus and rheumatoid arthritis * pregnancy or breastfeeding * taking drugs with the possibility of affecting the periodontal condition (calcium channel blockers, anticonvulsants, etc.) * Smoking * aggressive PD
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dental School, Periodontology Department
Babol, Iran
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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