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Laughing gas under the microscope: is it safe for heart patients?

NCT ID NCT00430989

First seen Jan 29, 2026 · Last updated May 19, 2026 · Updated 14 times

Summary

This study looked at whether using nitrous oxide (laughing gas) during major surgery is safe for people at risk of heart problems. Over 7,000 adults aged 45 and older were randomly assigned to receive either nitrous oxide or a similar gas without nitrous oxide. The researchers tracked deaths and serious heart events like heart attack, stroke, and cardiac arrest for 30 days after surgery to compare the two groups.

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Contacts and locations

Locations

  • Alfred Hosptial

    Melbourne, Victoria, 3004, Australia

Conditions

Explore the condition pages connected to this study.