Laughing gas under the microscope: is it safe for heart patients?
NCT ID NCT00430989
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether nitrous oxide (laughing gas) is safe for people with heart disease risk factors who need major surgery. Over 7,000 adults aged 45 and older were randomly assigned to receive either nitrous oxide or a gas without it during anesthesia. The researchers tracked deaths and heart-related problems like heart attack, stroke, and heart failure for 30 days after surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alfred Hosptial
Melbourne, Victoria, 3004, Australia
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