Could laughing gas lift the fog of Late-Life depression?
NCT ID NCT05007028
First seen Nov 24, 2025 · Last updated May 19, 2026 · Updated 26 times
Summary
This study looked at whether a one-hour treatment with nitrous oxide (laughing gas) can quickly reduce depression symptoms in older adults (ages 60-90) whose depression hasn't improved with standard medications. Sixty participants received either the gas or a placebo (medical air). Researchers measured changes in depression scores and brain activity over two weeks to see if this safe, fast-acting approach could offer relief.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University Hospital of Tours
Tours, 37044, France
Conditions
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