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Beetroot rinse may alter oral microbiome, tiny study hints

NCT ID NCT06588049

Knowledge-focused Sponsor: Dalhousie University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether rinsing with beetroot powder (rich in nitrates) for two weeks changes the types of bacteria in the mouth. Twenty-one healthy adults aged 18 to 40 used either a beetroot rinse or plain water daily. Researchers measured changes in oral bacteria, blood pressure, and nitric oxide levels.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Beetroot powder mouth rinse
What this could lead to
If it works, this could point toward a simple way to improve oral health or blood pressure through diet.
What could go wrong
This is a very small, early study with only 21 participants. It may not show clear results or apply to people with health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

21 people

The number who actually took part.

Started

Aug 2024

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * You are between the ages of 18 and 40. Have no uncontrolled systemic diseases. Participants with mild chronic conditions such as: * Asthma * Type 1 Diabetes Mellitus Exclusion Criteria: * You are under the age of 18. * You have uncontrolled systemic diseases, or acute infections. * You are taking prescription, antibiotics, probiotics, or antimicrobial mouthrinses. * You have a documented true allergy (i.e Hives, Swelling of lips/throat) Soy, Nuts, Seeds, Dairy, Egg products, Fish/Shellfish or Wheat. * The presence of acute or chronic oral conditions including: * Herpes Simplex Virus (recent cold sores) * Stomatitis * Oral Lichen Planus * Angular Cheilitis * Candidiasis * Necrotizing Gingival Diseases * Other inflammatory or infectious pathologies * Active dental caries "cavities" * Any other periodontal diagnosis other than 'Healthy Periodontium' or localized gingivitis

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nitric oxide Oral microbiome

Contacts and locations

Locations

  • Dalhousie University

    Halifax, Nova Scotia, B3H4R2, Canada

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