Light-Based brain imaging may unlock secrets of infantile seizures
NCT ID NCT02899832
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses a non-invasive light-based technique called near-infrared spectroscopy (NIRS) combined with EEG to measure blood flow changes in the brains of children aged 3 to 6 years during infantile epilepsy spasms. The goal is to better understand what happens in the brain before, during, and after these seizures. The research is purely observational and does not test any new treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand what happens in the brain during infantile spasms, potentially improving diagnosis and treatment monitoring.
- What could go wrong
- This is a small, early-stage observational study with only 14 children, so results may not apply to all patients. It does not test a treatment, so it will not directly improve outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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14 people
The number who actually took part.
- Started
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Feb 2013
- Finished
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Feb 2020
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Children between 3 and 6 years old presenting infantile spasms
- Ages
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3 to 6 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children between 3 and 6 years old presenting infantile spasms according to the Classification of the International League Against Epilepsy Exclusion Criteria: * Children younger than 3 months and older than 6 years of age, refusal of one of the parents, and dermatosis of the scalp
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Amiens
Amiens, 80054, France
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Fondation Ophtalmologique Rothshild
Paris, 75019, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can video games rewire young brains after injury?
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- Epilepsy drug candidate put to the test in healthy volunteers