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New drug showdown: can nipocalimab beat efgartigimod for muscle weakness?

NCT ID NCT07217587

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 31 times

Summary

This study tests whether nipocalimab works better than efgartigimod for people with generalized myasthenia gravis, a condition where the immune system attacks nerve-muscle connections, causing weakness. About 115 adults will receive one of the two drugs to see which better controls symptoms and improves daily activities. The goal is to manage the disease long-term, not cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advanced Neurology of Colorado

    RECRUITING

    Fort Collins, Colorado, 80528, United States

  • Atrium Health Wake Forest Baptist

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

  • HOCH Health Ostschweiz Kantonsspital St.Gallen

    RECRUITING

    Sankt Gallen, 9007, Switzerland

  • HSHS St. Elizabeth's Hospital

    RECRUITING

    O'Fallon, Illinois, 62269, United States

  • Henry Ford Hospital

    RECRUITING

    Detroit, Michigan, 48202, United States

  • Rambam Medical Center

    RECRUITING

    Haifa, 3109601, Israel

  • SFM Clinical Research LLC

    RECRUITING

    Boca Raton, Florida, 33487, United States

  • Sourasky Medical Center

    RECRUITING

    Tel Aviv, 6423906, Israel

  • Texas Neurology

    RECRUITING

    Dallas, Texas, 75206, United States

  • The Neurology Group

    RECRUITING

    Pomona, California, 91767, United States

  • University of Connecticut

    RECRUITING

    Farmington, Connecticut, 06030, United States

  • Velocity Clinical Research, Inc.

    RECRUITING

    Raleigh, North Carolina, 27607 6010, United States

Conditions

Explore the condition pages connected to this study.