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Double trouble: can stronger nicotine meds help you quit both cigarettes and E-Cigs?

NCT ID NCT06087328

Symptom relief Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether higher doses of nicotine patches and lozenges help people quit both smoking and vaping. 46 adults who used both cigarettes and e-cigarettes daily took part. Researchers measured how many days they stayed away from both products and checked for side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

46 people

The number who actually took part.

Started

Dec 2023

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18yrs + * Daily nicotine-containing e-cigarette user (25+ days per previous month) * E-cigarette use 5+ times/day * E-cigarette use \> 1year * Smoking \>1 cigarette on 5-7 days per week * Interest in quitting smoking and e-cigarette within the next month (\>7 on 10-point scale) * Willingness to use NRT * Able to receive text messages/email * Mailing address in South Carolina. Exclusion Criteria: * Medical conditions contraindicated to NRT use (including pregnancy, past month myocardial infarction, current cardiac arrhythmia, current angina, uncontrolled vascular disease, or medical conditions in which consumption of phenylalanine is contraindicated) * Individuals reporting current use of other nicotine-containing products and/or smoking cessation medications * Those who vape non-nicotine substances * Individuals unable to consent (e.g. significant cognitive deficit, non-English speaking).

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking Smoking Cessation Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cigarette smoking Electronic cigarette use Smoking cessation

Contacts and locations

Locations

  • Medical University of South Carolina - Charleston

    Charleston, South Carolina, 29403, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.