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Sound waves and a drug may fight brain cancer

NCT ID NCT07225621

First seen Nov 06, 2025 · Last updated Jun 19, 2026 · Updated 30 times

Summary

This study tests an experimental treatment for glioblastoma, a serious brain cancer. It combines a drug (5-ALA) with a special ultrasound device that aims to target cancer cells without surgery. About 103 people who have completed standard therapy will be randomly assigned to get the active treatment or a sham version. Both groups will also receive standard chemotherapy. The goal is to see if this approach helps people live longer without their cancer growing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Albany Medical Center

    RECRUITING

    Albany, New York, 12208, United States

    Contact

  • Columbia University

    RECRUITING

    New York, New York, 10032, United States

    Contact Email: •••••@•••••

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Email: •••••@•••••

  • Dent Neurologic Institute

    RECRUITING

    Buffalo, New York, 14226, United States

    Contact Email: •••••@•••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • New York Langone

    RECRUITING

    New York, New York, 10016, United States

    Contact Email: •••••@•••••

  • Northwell Health

    RECRUITING

    Long Island City, New York, 11030, United States

    Contact

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Email: •••••@•••••

  • Penn State Milton S. Hershey Medical Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact

  • University of Rochester

    RECRUITING

    Rochester, New York, 19642, United States

    Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.