New hope for tough brain cancer: drug cocktail targets recurrent lymphoma
NCT ID NCT07191431
First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 26 times
Summary
This study tests a combination of three drugs (orelabrutinib, selinexor, and either methotrexate or alternatives) for people with central nervous system lymphoma that has returned or not responded to prior therapy. The goal is to see if this mix can shrink tumors and delay progression. About 25 adults aged 14-80 will receive the treatment in 3-week cycles, with possible maintenance therapy. This is an early-stage, single-arm trial, so results will be compared to historical data.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LYMPHOMA CNS are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.