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New tooth gel could zap sensitivity pain

NCT ID NCT06378255

Symptom relief Sponsor: Peking University Hospital of Stomatology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new gel-like desensitizer for people with sensitive teeth. 40 adults received either the new polycation-based desensitizer or a standard one. Researchers measured pain relief from touch and cold air. The goal was to see if the new gel safely reduces tooth sensitivity better than current options.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
polycation-based dental desensitizer
What this could lead to
If it works, this could provide a new, effective option for people with sensitive teeth to reduce pain from hot, cold, or touch.
What could go wrong
This is a small, completed trial with only 40 participants. The results may not apply to everyone, and the new desensitizer may not work better than existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Mar 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Dentin Hypersensitivity, with Vas score≥4 points and the normal pulp viability * dentin-sensitive tooth in at least 2 different quadrants of the mouth (neck enamel dentin exposure or maxillofacial abrasion within the middle layer of dentin). * in good overall health * participants informed consent. Exclusion Criteria: * gastroesophageal reflux * Dental caries, wedge defects, crowns or large fillings. * Received dentin sensitivity desensitization treatment or used desensitization mouthwash within 1 month. * Received systematic periodontal therapy or periodontal surgery within 3 months, ongoing orthodontic treatment, and medical treatment, including long-term use of anti-inflammatory, analgesic, and psychotropic medications. * Pregnancy or breastfeeding. * Participated in other clinical trials in the past 3 months.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dentin sensitivity

Contacts and locations

Locations

  • Peking University School and Hospital of Stomatology

    Beijing, Beijing Municipality, 100081, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.