New toothpaste study aims to soothe sensitive teeth

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant demonstrates understanding of the study and is willing to participate as evidenced by voluntary written informed consent and has received a signed and dated copy of the informed consent form. * Participant is 18 to 60 years of age. * Participant understands and is willing, able and likely to comply all study procedures and restrictions. * Participant with good general and mental health, in the opinion of the investigator or medically qualified designee: 1. No clinically significant and relevant abnormalities of medical history or physical /oral examination. 2. Absence of any condition that would impact on the participant's safety or wellbeing or affect the participant's ability to understand and follow study procedures and requirements. * Self-reported history of DH lasting more than 6 months but not more than 10 years and minimum of 20 natural teeth. Exclusion Criteria: * Female participant who is known to be pregnant or who is intending to become pregnant over the duration of the study. * Female participant who is breast-feeding. * Participant with known or suspected intolerance or hypersensitivity to the study materials (or closely related compounds) or any of their stated ingredients. * Participation is in another clinical study or receipt of an investigational drug within 30 days prior to the screening visit. * Participant who has had tooth desensitizing treatment within 8 weeks of Screening visit (professional sensitivity treatments and non-dentifrice sensitivity treatments). * Participant who had previously participated in this study. * Participant with a recent history (within the last year) of alcohol or other substance abuse. * Participant who is an employee of the sponsor or the study site or members of their immediate family. * Participant with presence of chronic debilitating disease which, in the opinion of the investigator, could affect study outcomes. * Participant with any condition or daily doses of a medication which, in the opinion of the investigator, is causing xerostomia. * Participant with dental prophylaxis within 4 weeks of screening. * Participant with tongue or lip piercing or presence of dental implants. * Participant with gross periodontal disease, treatment of periodontal disease (including surgery) within 12 months of screening, scaling or root planning within 3 months of screening. * Participant who did teeth bleaching within 8 weeks of screening. * Participant with Specific Dentition Exclusions for Test teeth. 1. Tooth with evidence of current or recent caries, or reported treatment of decay in 12 months of screening. 2. Tooth with exposed dentine but with deep, defective or facial restorations, teeth used as abutments for fixed or removable partial dentures, teeth with full crowns or veneers, orthodontic bands or cracked enamel. Sensitive teeth with contributing aetiologies other than erosion, abrasion or recession of exposed dentine. 3. Sensitive teeth are not expected, in the opinion of the investigator, to respond to treatment with an over-the-counter dentifrice. * Participant who has used product of a sensitivity dentifrice within 8 weeks of screening. * Participant who had daily doses of a medication or traditional herbal ingredients or treatments which, in the opinion of the investigator, could interfere with the perception of pain. Examples of such medications include analgesics, anticonvulsants, antihistamines that cause marked or moderate sedation, sedatives, tranquilizers, mood-altering and anti-inflammatory drugs. Examples of herbal ingredients/treatments include clove oil, olive oil, or other treatments that are directly applied to the oral cavity for the treatment of oral health problems. * Participant who is currently taking a course of antibiotics or has taken a course of antibiotics within 2 weeks of baseline. * Participant who had dental procedures or participant who require antibiotic prophylaxis for dental procedures. * Any participant who, in the opinion of the investigator, should not participate in the study.