New rectal cancer device could spare elderly patients from surgery
NCT ID NCT04336202
First seen Apr 29, 2026 · Last updated Jun 23, 2026 · Updated 9 times
Summary
This pilot study tests a new rectal applicator for brachytherapy in 45 elderly patients with inoperable rectal cancer. Participants receive external beam radiotherapy followed by three brachytherapy treatments using the new device. The study aims to see if the device is feasible, safe, and effective at controlling the tumor, while monitoring for severe side effects.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Jewish General Hospital
Montreal, Quebec, H3T 1E2, Canada
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
External beam radiotherapy and endorectal brachytherapy using a new rectal applicator
What this could lead to
If successful, this could offer a safer, more effective radiation treatment option for elderly patients with inoperable rectal cancer, potentially improving quality of life and tumor control.
What could go wrong
This is a small pilot study with only 45 participants and is currently suspended. The new device may cause severe side effects like rectal bleeding or diarrhea, and the trial has strict stopping rules for toxicity.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.