Inoperable disease
Clinical trials for Inoperable disease explained in plain language.
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New triple-drug attack aims to revive immune response in hard-to-treat melanoma
Disease control OngoingThis phase 2 trial tests whether combining high-dose interleukin-2 with low-dose ipilimumab, followed by nivolumab, can shrink tumors in people with advanced melanoma that has stopped responding to prior immunotherapy. About 29 participants with inoperable stage III or IV melanom…
Matched conditions: INOPERABLE DISEASE
Phase 2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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New rectal cancer device tested in elderly patients
Disease control PausedThis pilot study tests a new rectal applicator for delivering radiation therapy to elderly patients with inoperable rectal cancer. The treatment combines external beam radiation with three sessions of internal radiation (brachytherapy) using the new device. The study aims to see …
Matched conditions: INOPERABLE DISEASE
Sponsor: Sir Mortimer B. Davis - Jewish General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Blue dye cream takes on tough skin cancer in new trial
Disease control By invitation onlyThis study tests a cream made from methylene blue, a common dye, on people with advanced basal cell carcinoma (a type of skin cancer) that cannot be treated with surgery or radiation. Twenty adults will apply the cream to their tumors every two days for one month. Researchers wil…
Matched conditions: INOPERABLE DISEASE
Phase 3 • Sponsor: Daryoush Hamidi Alamdari, PhD • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Blue dye gel shows promise for treating inoperable skin cancer
Disease control By invitation onlyThis study tests whether a special blue dye gel (methylene blue) can safely shrink skin cancer tumors and help wounds heal in people who cannot have surgery or radiation. About 20 adults with advanced squamous cell carcinoma will apply the gel every two days for a month, followed…
Matched conditions: INOPERABLE DISEASE
Phase 3 • Sponsor: Daryoush Hamidi Alamdari, PhD • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC