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Nerve-Stretching technique may ease sciatica pain — trial puts it to the test

NCT ID NCT07752199

Symptom relief Sponsor: Longhua Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This trial tests whether adding neural mobilization—a gentle, controlled leg movement technique—to standard manual therapy can improve pain, function, and quality of life in people with lumbar disc herniation and sciatica. About 72 adults aged 18–65 with unilateral leg symptoms will receive either manual therapy plus neural mobilization or manual therapy plus a sham version, over three weeks. Researchers will measure changes in disability, pain, quality of life, inflammatory markers, and skin temperature patterns to see if the nerve-focused approach offers extra benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Neural mobilization (a gentle, controlled leg movement technique) combined with manual therapy
What this could lead to
If it works, this could point toward a more effective non-surgical treatment for sciatica and lumbar disc herniation, potentially reducing pain and improving mobility without medication or surgery.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. The added benefit of neural mobilization over manual therapy alone is uncertain, and the technique may not work for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

72 people

The number who actually took part.

Started

Apr 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Participants will be eligible for inclusion if they meet the following criteria: Adults aged 18-65 years. Diagnosis of lumbar disc herniation based on clinical symptoms and imaging findings. Presence of unilateral lumbar radiculopathy. Persistent symptoms despite initial conservative management. Ability to participate in the intervention protocol. Provided written informed consent before study enrollment. Exclusion Criteria: \- Participants will be excluded if they meet any of the following criteria: Requirement for surgical intervention for lumbar disc herniation. Serious spinal conditions, including spinal infection, tumor, or fracture. Severe systemic diseases or acute inflammatory conditions. Pregnancy or breastfeeding. Receipt of other interventions that may affect study outcomes during the study period.

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Conditions

The condition(s) this trial relates to.

Intervertebral Disc Displacement sciatica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Herniated disc Sciatica due to intervertebral disc disorder

Contacts and locations

Locations

  • Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine

    Shanghai, 200032, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.