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Brain scans reveal how a brief crisis plan may lower suicide risk

NCT ID NCT05275101

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a one-hour crisis response planning session can reduce suicide risk more than standard care. 191 adults with current suicidal thoughts were randomly assigned to either the crisis plan or usual risk management. Researchers used brain scans and surveys to measure changes in emotion, behavior, and suicide risk over six months.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

191 people

The number who actually took part.

Started

Jul 2021

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Generally medically and neurologically healthy * Age 18 years or older at the time of consent * Willing and able to give informed consent * Individuals in the acutely suicidal group: endorse current suicide intent as indicated by a total score of 5 or greater on the Beck's Scale for Suicidal Ideation. Exclusion Criteria: * Medical or neurologic condition or neurocognitive dysfunction that would interfere with the study * Current or past manic/hypomanic episode, schizophrenia, or psychotic symptoms * Deafness in either ear * Currently pregnant or trying to become pregnant * Electroconvulsive therapy (ECT) within the past 6 months * Current moderate to severe substance use disorder * Lack of fluency in English * Positive alcohol breathalyzer test and/or acute drug intoxication the day of the fMRI scans * Unwilling or unable to sign the informed consent document * Under 18 years old at the time of enrollment * Traumatic brain injury from a suicide attempt or another event * Presence of ferrous-containing metals within the body * Inability to tolerate small, enclosed spaces without significant anxiety * Individuals enrolled as controls: no lifetime history of any DSM-5 disorder * Individuals enrolled as controls: no lifetime history of suicide ideation or intent

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Conditions

The condition(s) this trial relates to.

Suicide Suicide Prevention

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ohio State University

    Columbus, Ohio, 43210, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.