Brain scans reveal how a brief crisis plan may lower suicide risk
NCT ID NCT05275101
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a one-hour crisis response planning session can reduce suicide risk more than standard care. 191 adults with current suicidal thoughts were randomly assigned to either the crisis plan or usual risk management. Researchers used brain scans and surveys to measure changes in emotion, behavior, and suicide risk over six months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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191 people
The number who actually took part.
- Started
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Jul 2021
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Generally medically and neurologically healthy * Age 18 years or older at the time of consent * Willing and able to give informed consent * Individuals in the acutely suicidal group: endorse current suicide intent as indicated by a total score of 5 or greater on the Beck's Scale for Suicidal Ideation. Exclusion Criteria: * Medical or neurologic condition or neurocognitive dysfunction that would interfere with the study * Current or past manic/hypomanic episode, schizophrenia, or psychotic symptoms * Deafness in either ear * Currently pregnant or trying to become pregnant * Electroconvulsive therapy (ECT) within the past 6 months * Current moderate to severe substance use disorder * Lack of fluency in English * Positive alcohol breathalyzer test and/or acute drug intoxication the day of the fMRI scans * Unwilling or unable to sign the informed consent document * Under 18 years old at the time of enrollment * Traumatic brain injury from a suicide attempt or another event * Presence of ferrous-containing metals within the body * Inability to tolerate small, enclosed spaces without significant anxiety * Individuals enrolled as controls: no lifetime history of any DSM-5 disorder * Individuals enrolled as controls: no lifetime history of suicide ideation or intent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ohio State University
Columbus, Ohio, 43210, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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