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New pain block technique could slash opioid use after jaw surgery

NCT ID NCT05351151

Symptom relief Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether ultrasound-guided nerve blocks in the jaw could reduce pain and opioid use after maxillomandibular osteotomy (jaw realignment surgery). Fifty patients aged 15 to 45 were enrolled. One group received nerve blocks with ropivacaine, while the other had standard lidocaine injections at incision sites. The main goal was to measure opioid consumption in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ropivacaine and Lidocaine (local anesthetics)
What this could lead to
If effective, this approach could reduce the need for strong painkillers like opioids after jaw surgery, leading to fewer side effects and faster recovery.
What could go wrong
This is a small, completed study with only 50 participants. The results may not apply to all patients or surgeries, and nerve blocks carry risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

May 2022

Finished

Mar 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients from 15 to 45 years old, * Scheduled for maxillary-mandibular osteotomy, * Registered in French social insurance register, * With informed consent disclosure. Exclusion Criteria: * American Society of Anesthesiologists (ASA) classification ≥ 3 * Innate or acquired hemostasis pathology, * Peripheric neuropathy, * Drug intake for chronic pain, * Infection/scar at needle insertion site, * Associated rhinoplasty surgery, * Allergy to local anesthetics, * Pregnant woman or potentially, * Breastfeeding woman, * Already registered in other clinical trial, * Adults under legal protection of incapable adult, * Cognitive disease impairing using of evaluation tools performed in protocol, * All contraindication of anesthetics drugs used in protocol.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain post operative Regional anesthesia

Contacts and locations

Locations

  • University Hospital of Toulouse

    Toulouse, 31100, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.