Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Nerve blocks slash pain after keyhole heart surgery

NCT ID NCT03743194

Symptom relief Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether injecting a long-lasting numbing medicine (liposomal bupivacaine) near the chest muscles could reduce pain after minimally invasive heart surgery. 210 adults having robot-assisted mitral valve repair took part. The main goal was to see if the nerve blocks improved a combined pain and side-effect score over the first three days after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

210 people

The number who actually took part.

Started

Dec 2021

Finished

Mar 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. 18-85 years old; 2. Elective minimally invasive robotically-assisted mitral valve repair via anterolateral thoracotomy Exclusion Criteria: 1. Weight less than 50 kg; 2. Pregnancy or lactation; 3. Emergency surgery and patients transferred from the ICU to the operating room; 4. Redo cardiothoracic surgery or post-operative reoperation within 72 hours of index procedure (including minor chest wall procedures including tube thoracostomy, thoracentesis or percutaneous drain placement); 5. Anticipated endotracheal intubation \> 24 hours; 6. Anticipated non-study nerve block that provides analgesia to the intercostal nerves; 7. Active systemic or cardiopulmonary infection; 8. Mechanical circulatory support; 9. Allergy or contraindication to study local anesthetics; 10. Current chronic pain or routine opioid use (patients on chronic enteral opioids like Percocet or Vicodin) in a dose of \> 30 mg of morphine-milligram-equivalents for at least 10 days in last 30 days; 11. Poorly controlled psychiatric disorders; 12. Clinically important current neurologic deficit; 13. Active liver disease or cirrhosis; 14. Pacemaker generator or breast implants ipsilateral to surgery; 15. Previous participation in this study.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Post operative pain control are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post operative pain control

Contacts and locations

Locations

  • The Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.