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New study aims to ease pain and improve breathing after gallbladder surgery
NCT ID NCT07666646
First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 3 times
Summary
This study compares two types of nerve blocks—erector spinae plane block and modified thoracoabdominal nerve block—to see which one works better for pain control and lung function after laparoscopic gallbladder removal. Sixty adults having elective surgery will be randomly assigned to receive one of the two blocks. The goal is to find a method that reduces pain and opioid use while helping patients breathe easier after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- local anesthetic (bupivacaine or similar)
- What this could lead to
- If one block works better, it could mean less pain, better breathing, and less need for strong painkillers after gallbladder surgery.
- What could go wrong
- This is a small, early-stage trial with only 60 people. Results may not apply to everyone, and nerve blocks carry small risks like infection or bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18-70 years * American Society of Anesthesiologists (ASA) physical status I-III * Patients scheduled for elective laparoscopic cholecystectomy * Patients who provide written informed consent * Patients who are able to cooperate and perform pulmonary function tests (PFTs) Exclusion Criteria: * Coagulation disorders or anticoagulant therapy contraindicating regional anesthesia * Infection at the planned block site * Known allergy to local anesthetic agents * Conversion to open surgery * Hemodynamic instability * Inability to cooperate with pulmonary function tests (PFTs) * Pre-existing severe pulmonary disease (e.g., severe chronic obstructive pulmonary disease or restrictive lung disease) * Chronic opioid use or opioid dependence * Pregnancy or breastfeeding * Active smokers * Body mass index (BMI) \> 35 kg/m²
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kayseri City Hospital
RECRUITINGKayseri, Kocasinan, 38080, Turkey (Türkiye)
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