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New pain block study aims to speed recovery after heart surgery

NCT ID NCT07417462

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 22, 2026 · Updated 4 times

Summary

This study tests two different nerve blocks to see which one better controls pain after open-heart surgery. 90 adults aged 40-60 having coronary bypass will get one of the blocks or a sham procedure. The goal is to reduce pain and the need for extra painkillers, helping patients recover more smoothly.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine and dexamethasone
What this could lead to
If one block works better, it could become the standard way to manage pain after open-heart surgery, helping patients recover faster with less medication.
What could go wrong
This is a small, early-stage trial with only 90 people, so results may not apply to everyone. The blocks might not reduce pain significantly more than a sham procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age from 40 to 60 years. * Both sexes. * American Society of Anesthesiology (ASA) physical status II-III. * Body mass index (BMI) \< 35 kg/m2. * Underwent cardiac surgery (coronary artery bypass graft surgery with median sternotomy). Exclusion Criteria: * Valve replacement procedures. * Emergency operations. * Redo surgeries. * Minimally invasive approaches. * The presence of psychiatric disorders. * Cognitive impairment preventing accurate assessment using the verbal numerical rating scale (NRS). * Known hypersensitivity or a history of allergy to local anesthetics. * Had severe major organ dysfunction. * Left ventricular ejection fraction below 30%. * Pregnancy or breastfeeding.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiac surgery Enhanced recovery Pecto-intercostal fascial block Transversus thoracic muscle plane block

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Assiut University

    RECRUITING

    Asyut, 71515, Egypt

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