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Nerve block showdown: which eases hip replacement pain best?

NCT ID NCT07445009

Symptom relief Sponsor: Fatih Sultan Mehmet Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at two types of ultrasound-guided nerve blocks for pain after hip replacement surgery in 62 patients aged 65 and older. One group got a PENG block plus a lateral femoral cutaneous nerve block, the other got a PENG block plus a lumbar erector spinae plane block. The goal was to see which approach led to better recovery quality, less pain, and fewer complications like delirium.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If one nerve block proves better, it could improve pain control and recovery after hip replacement in elderly patients.
What could go wrong
This is a small, completed observational study, not a large trial. Results may not apply to all patients, and nerve blocks carry risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

62 people

The number who actually took part.

Started

Jul 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Elderly patients (≥65 years) undergoing elective partial or total hip arthroplasty under general anesthesia at Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 65 years or older * ASA physical status I-III * Scheduled for elective partial or total hip arthroplasty under general anesthesia * Mini-Mental State Examination (MMSE) score ≥24 * Written informed consent obtained Exclusion Criteria: * MMSE score below 24 * Refusal to participate * Known allergy to local anesthetics or study medications * Coagulation disorders or anticoagulant use contraindicating regional block * Infection at the block site * Pre-existing chronic pain conditions requiring opioid therapy * ASA physical status IV or above

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Conditions

The condition(s) this trial relates to.

Emergence Delirium hip fracture Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hip arthroplasty Hip fractures Postoperative delirium (POD) Postoperative pain

Contacts and locations

Locations

  • Istanbul Provincial Health Directorate Fatih Sultan Mehmet Training and Research Hospital

    Istanbul, 34000, Turkey (Türkiye)

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