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New nerve block combo may ease heart surgery pain

NCT ID NCT06285773

Symptom relief Sponsor: Medipol University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding a recto-intercostal fascial plane block (RIFPB) to a standard pecto-intercostal fascial plane block (PIFPB) improves pain control after open-heart surgery. Forty adults scheduled for heart surgery received both blocks with the anesthetic bupivacaine. Researchers measured pain scores and recovery quality over 24 hours, and tracked how much extra pain medication was needed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine (marcaine)
What this could lead to
If effective, this combination of nerve blocks could provide better pain control after heart surgery, reducing the need for strong painkillers like tramadol.
What could go wrong
This is a small, completed study with only 40 participants. Results may not apply to all heart surgery patients, and nerve blocks carry risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Feb 2024

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * American Society of Anesthesiologists (ASA) classification I-III * Scheduled for cardiac surgery with elective median sternotomy under general anesthesia Exclusion Criteria: * a personal or family history of malignant hyperthermia, * opioid sensitivity, * alcohol or drug addiction, * liver or kidney disease, * skin infection in the area to be blocked, * thoracic deformity, * patients who are allergic to their medications, * patients who do not agree to participate

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Conditions

The condition(s) this trial relates to.

coronary artery disorder heart disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiac disease

Contacts and locations

Locations

  • Istanbul Medipol University Hospital

    Istanbul, Bagcilar, 34070, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.