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Nerve block may cut opioid needs after hysterectomy

NCT ID NCT07046949

Symptom relief Sponsor: Yuri Semenyuk Rivne Regional Clinical Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a nerve block called the anterior quadratus lumborum block, given before surgery, can reduce pain and the need for opioids in women undergoing abdominal hysterectomy. 56 participants were randomly assigned to receive either the nerve block plus standard care or standard care alone. The researchers measured pain levels, opioid use, and recovery quality after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
anterior quadratus lumborum block (a nerve block injection)
What this could lead to
If it works, this could offer a way to reduce pain and opioid use after hysterectomy, leading to faster recovery.
What could go wrong
This is a small, completed trial with only 56 participants. The nerve block may not actually reduce pain or opioid needs, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Jul 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 55 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients with ASA status I-II * patients with symptomatic fibroids * patients scheduled for abdominl hysterectomy Exclusion Criteria: * refusal to participate in the study at any of its stages * ASA class ≥ III * body mass index \> 40 kg/m2 * use of opiate receptor agonists/antagonists before surgery * uncontrolled hypertension

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia Chronic Pain leiomyoma Postoperative Nausea and Vomiting tumor of uterus uterine cancer uterine corpus leiomyoma uterine disorder Uterine Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Uterine bleeding Uterine diseases Uterine fibroids Uterine neoplasms

Contacts and locations

Locations

  • Yuri Semenyuk Rivne regional cinical hospital

    Rivne, Rivne Oblast, 33007, Ukraine

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