Nerve block may cut opioid needs after hysterectomy

NCT ID NCT07046949

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a nerve block called the anterior quadratus lumborum block, given before surgery, can reduce pain and the need for opioids in women undergoing abdominal hysterectomy. 56 participants were randomly assigned to receive either the nerve block plus standard care or standard care alone. The researchers measured pain levels, opioid use, and recovery quality after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

anterior quadratus lumborum block (a nerve block injection)

What this could lead to

If it works, this could offer a way to reduce pain and opioid use after hysterectomy, leading to faster recovery.

What could go wrong

This is a small, completed trial with only 56 participants. The nerve block may not actually reduce pain or opioid needs, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia Chronic Pain leiomyoma Postoperative Nausea and Vomiting tumor of uterus uterine cancer uterine corpus leiomyoma uterine disorder Uterine Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Yuri Semenyuk Rivne regional cinical hospital

    Rivne, Rivne Oblast, 33007, Ukraine