Which nerve block wins for hysterectomy pain?
NCT ID NCT05656872
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared two ultrasound-guided nerve blocks for pain after open hysterectomy: the transversus abdominis plane (TAP) block and the ilioinguinal-iliohypogastric (IIH) block. 42 adults having elective surgery were randomly assigned to one block. The main goal was to see which block delayed the need for rescue pain medication longer. The study also measured total painkiller use and pain scores.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block procedure
- What this could lead to
- If one nerve block proves better, it could improve pain control after hysterectomy and reduce the need for strong painkillers.
- What could go wrong
- This is a small, completed study with only 42 participants. Results may not apply to all patients or surgeries, and nerve blocks carry rare risks like infection or bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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42 people
The number who actually took part.
- Started
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Nov 2022
- Finished
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Apr 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
35 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants will be adult patients (35-65 years) * ASA I-III * Scheduled for elective open TAH Exclusion Criteria: * Patient refusal * BMI \> 40 kg·m-² * Pregnancy * Chronic pain requiring daily analgesics * Any known allergy to local anesthetic, nalbuphine, paracetamol, or diclofenac * Patients with neurological, psychological disorders or those lacking cooperation * Patients with anatomic abnormalities at site of injection, skin lesions or wounds at site of proposed needle insertion. * Patients with bleeding disorders defined as (INR \>2) and/ or (platelet count \<100,000/µL) * Patients with hepatic disease e.g. liver cell failure or hepatic malignancy or hepatic enlargement
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Medicine, Cairo University
Cairo, Cairo Governorate, Egypt
-
Mohamed Ollaek
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a nerve block stop pain months after hysterectomy?