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New combo therapy before surgery aims to boost stomach cancer outcomes

NCT ID NCT07059299

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This early-phase trial tests a new combination of the immunotherapy drug tislelizumab plus standard chemotherapy (FLOT) given before surgery for patients with resectable stomach, esophageal, or gastroesophageal junction cancer. The goal is to see if this approach is safe and effective enough to warrant larger studies. About 18 adults with locally advanced but removable tumors will receive up to 8 cycles of the combo before surgery, instead of the usual 4 cycles before and 4 after.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hämatologisch-Onkologische Praxis Eppendorf (hope)

    NOT_YET_RECRUITING

    Hamburg, 20249, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Klinikum rechts der Isar München der TU München

    RECRUITING

    München, 81675, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Krankenhaus Nordwest GmbH Institut für Klinisch-Onkologische Forschung (IKF)

    RECRUITING

    Frankfurt, 60488, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Leipzig

    NOT_YET_RECRUITING

    Leipzig, 04103, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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