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New combo aims to boost Pre-Surgery treatment for stomach cancer

NCT ID NCT07059299

Recruiting now Disease control Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests a new combination of the immunotherapy drug tislelizumab plus standard chemotherapy (FLOT) given before surgery for people with stomach, esophageal, or gastroesophageal junction cancer that can be removed. The goal is to see if this longer pre-surgery treatment is safe and works well enough to study further. About 18 adults with locally advanced, resectable cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Adenocarcinoma Of Esophagus esophageal adenocarcinoma gastric adenocarcinoma gastric neoplasm gastroesophageal adenocarcinoma gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESOPHAGEAL ADENOCARCINOMA ESOPHAGOGASTRIC JUNCTION ADENOCARCINOMA GASTRIC ADENOCARCINOMA NEOADJUVANT THERAPY RESECTABLE ESOPHAGOGASTRIC ADENOCARCINOMA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hämatologisch-Onkologische Praxis Eppendorf (hope)

    NOT_YET_RECRUITING

    Hamburg, 20249, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Klinikum rechts der Isar München der TU München

    RECRUITING

    München, 81675, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Krankenhaus Nordwest GmbH Institut für Klinisch-Onkologische Forschung (IKF)

    RECRUITING

    Frankfurt, 60488, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Leipzig

    NOT_YET_RECRUITING

    Leipzig, 04103, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact