New drug cocktail shows promise against advanced melanoma before surgery
NCT ID NCT03554083
First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 29 times
Summary
This study tested whether giving a combination of targeted drugs (vemurafenib and cobimetinib) and an immunotherapy (atezolizumab) before surgery could help patients with high-risk stage III melanoma. 64 adults with advanced melanoma that had spread to lymph nodes took part. The goal was to see if the treatment could shrink or eliminate tumors before surgical removal, potentially reducing the risk of the cancer coming back.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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University of Minnesota/Masonic Cancer Center
Minneapolis, Minnesota, 55455, United States
Conditions
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