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Can a Contrast-Free MRI match ultrasound for spotting Stroke-Causing blockages?

NCT ID NCT07756775

Diagnosis Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This study looks at 200 adults who have had an ischemic stroke or transient ischemic attack (TIA). Each participant will receive two types of imaging: a non-contrast magnetic resonance angiography (NC-MRA) and a carotid Doppler ultrasound. The goal is to see how well these two methods agree in detecting and grading narrowing of the carotid arteries, which is a major cause of stroke. The findings could help doctors choose the best imaging approach for evaluating stroke patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Non-contrast magnetic resonance angiography (NC-MRA) and carotid Doppler ultrasonography
What this could lead to
If NC-MRA proves as good as or better than carotid Doppler, it could become a preferred, safer imaging option for evaluating stroke patients, potentially improving diagnosis and treatment planning.
What could go wrong
This is an observational study, so it won't prove which method is better for patient outcomes. Results may not apply to all stroke patients, and NC-MRA may not be feasible for everyone due to MRI contraindications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (≥18 years) presenting to Sohag University Hospital with a clinical diagnosis of ischemic stroke or transient ischemic attack (TIA) who are eligible for magnetic resonance imaging and carotid Doppler ultrasonography.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Clinically diagnosed ischemic stroke or transient ischemic attack (TIA). * Imaging performed within 7-14 days of symptom onset. * Hemodynamically stable and suitable for magnetic resonance imaging (MRI). * Able and willing to provide written informed consent. Exclusion Criteria: * Hemorrhagic stroke. * Previous carotid artery stenting. * Contraindications to MRI, including: * Non-MRI-compatible pacemakers or other MRI-incompatible implants. * Cochlear implants. * MRI-incompatible metallic orthopedic implants. * Severe claustrophobia.

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Conditions

The condition(s) this trial relates to.

carotid stenosis ischemic stroke transient ischemic attack

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carotid artery stenosis (symptomatic and asymptomatic) Ischemic stroke Transient ischemic attack

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sohag University Hospital

    RECRUITING

    Sohag, Sohag Governorate, 82524, Egypt

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