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New ALS drug trial aims to slow nerve damage

NCT ID NCT07369076

First seen Feb 01, 2026 · Last updated May 22, 2026 · Updated 15 times

Summary

This trial tests an experimental drug called NB-4746 in 80 people with ALS. The study has two parts: first, a short safety check with low or high doses, then a longer 12-week test. Researchers will watch for side effects, measure how the drug moves in the body, and check a blood marker of nerve damage. Participants can continue treatment for up to a year after the main study.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Concord Repatriation General Hospital

    RECRUITING

    Concord, New South Wales, 2139, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Flinders Medical Centre

    RECRUITING

    Bedford Park, South Australia, 5042, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Genge Partners

    RECRUITING

    Montreal, Quebec, H4A 3T2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Neuroscience Research Australia

    RECRUITING

    Randwick, New South Wales, 2031, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Brisbane and Women's Hospital

    RECRUITING

    Brisbane, Queensland, 4029, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stan Cassidy Center for Rehabilitation

    RECRUITING

    Fredericton, New Brunswick, E3B 0C7, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.