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New hope for rare blood cancer: drug duo targets enlarged spleen

NCT ID NCT04468984

Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding the experimental drug navitoclax to the standard drug ruxolitinib can shrink the spleen and reduce symptoms better than other available treatments in adults with myelofibrosis that has returned or not improved. About 330 participants will be randomly assigned to receive either the combination or the best available therapy. The main goal is to see if the combination reduces spleen size by at least 35% after 24 weeks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 330 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2020

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Must complete the Myelofibrosis Symptom Assessment Form (MFSAF) v4.0 on at least 4 out of the 7 days immediately prior to the date of randomization and must agree to collect MFSAF data daily by ePRO device during the study collection window. \-- Has at least 2 symptoms each with an average score \>= 3 or an average total score of \>= 12, as measured by the MFSAF v4.0. * Documented diagnosis of primary myelofibrosis (MF) as defined by the World Health Organization (WHO) classification, post polycythemia vera (PPV)-MF, or post essential thrombocytopenia (PET)-MF, characterized by bone marrow fibrosis grades 2 or 3. * Classified as intermediate-2 or high-risk MF, as defined by the Dynamic International Prognostic Scoring System Plus (DIPSS+). * Must currently be on treatment or have received prior treatment with a single Janus Kinase 2 (JAK2) inhibitor, ruxolitinib, and meet one of the following criteria (in addition to the minimum splenomegaly and symptom burden also required for eligibility): * Treatment with ruxolitinib for \>= 24 weeks that was stopped due to lack of spleen response (refractory), or loss of spleen response or symptom control after a previous response (relapsed), or was continued despite relapsed/refractory status. * Treatment with ruxolitinib for \< 24 weeks with documented disease progression while on therapy as defined by any of the following: * Appearance of new splenomegaly that is palpable to at least 5 cm below the left costal margin (LCM) in participants with no evidence of splenomegaly prior to the initiation of ruxolitinib. * A \>= 100% increase in the palpable distance below the LCM in participants with measurable spleen distance 5 to 10 centimeters (cm) prior to the initiation of ruxolitinib. * A \>= 50% increase in the palpable distance below the LCM in participants with measurable spleen distance \> 10 cm prior to the initiation of ruxolitinib. * A spleen volume increase of \>= 25% (as assessed by Magnetic Resonance Imaging \[MRI\] or Computed Tomography \[CT\] scan) in participants with a spleen volume assessment prior to the initiation of ruxolitinib. * Prior treatment with ruxolitinib of at least 10 mg twice daily (BID) for \>= 28 days with intolerance defined as new RBC transfusion requirement (at least 2 units/month for 2 months) while receiving a total daily ruxolitinib dose of \>= 30 mg but unable to reduce dose further due to lack of efficacy. Note: Participant must not require a ruxolitinib dose less than 10 mg BID (20 mg daily) due to prior history of ruxolitinibrelated ≥ Grade 3 toxicity. * Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2. * Splenomegaly defined as palpable spleen measurement \>= 5 cm below left costal margin or spleen volume \>= 450 cm3 as assessed centrally by MRI or CT scan. * Baseline platelet count \>= 100 × 10\^9/L. Exclusion Criteria: * Received prior treatment with a B-cell lymphoma 2 homology 3 (BH3)-mimetic compound, bromodomain and extra-terminal (BET) inhibitor, phosphoinositide 3- kinase and telomerase inhibitors (e.g., parsaclisib), prior use of \> 1 JAK2 inhibitor or stem cell transplant. * Eligible for stem cell transplantation at the time of study entry. * Receiving medication that interferes with coagulation or platelet function within 3 days prior to the first dose of study drug or during the study treatment period except for low dose aspirin (up to 100 mg daily) and low molecular weight heparin (LMWH). * Receiving anticancer therapy for an active malignancy or MF including chemotherapy, radiation therapy, hormonal therapy such that at least 5 half-lives of that medication is completed at least 7 days prior to the first dose of study drug or within 30 days prior to first dose of study drug, whichever is shorter, and during the study treatment period (other than any overlapping therapy as part of the selected BAT).

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Conditions

The condition(s) this trial relates to.

myelofibrosis neoplasm primary myelofibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myelofibrosis (MF)

Contacts and locations

Locations

  • A.O.U. CITTA' DELLA SALUTE E DELLA SCIENZA DI TORINO - Ospedale Molinette /ID# 221223

    Turin, Piedmont, 10126, Italy

  • AOU Policlinico G. Rodolico - San Marco /ID# 219089

    Catania, 95123, Italy

  • ARS-MEDICAL Sp. z o.o. /ID# 238336

    Piła, Greater Poland Voivodeship, 64-920, Poland

  • ASST Papa Giovanni XXIII /ID# 221222

    Bergamo, 24127, Italy

  • ASST Sette Laghi - Ospedale Di Circolo E Fondazione Macchi Varese /ID# 234183

    Varese, 21100, Italy

  • AZ-Delta /ID# 221469

    Roeselare, West-Vlaanderen, 8800, Belgium

  • Aalborg University Hospital /ID# 224391

    Aalborg, North Denmark, 9000, Denmark

  • Acibadem City Clinic Tokuda University Hospital EAD /ID# 231649

    Sofia, 1407, Bulgaria

  • Alberts Cellular Therapy /ID# 231556

    Pretoria, Gauteng, 0044, South Africa

  • Almazov National Medical Research Centre /ID# 221114

    Saint Petersburg, 197341, Russia

  • American Oncology Partners of Maryland /ID# 222836

    Bethesda, Maryland, 20817, United States

  • Aomori Prefectural Central Hospital /ID# 221778

    Aomori, Aomori, 030-8553, Japan

  • Aotearoa Clinical Trials /ID# 232201

    Papatoetoe, Auckland, 2025, New Zealand

  • Atrium Health Wake Forest Baptist Medical Center /ID# 222899

    Winston-Salem, North Carolina, 27157-0001, United States

  • Augusta University Georgia Cancer Center /ID# 219051

    Augusta, Georgia, 30912-0003, United States

  • Augusta-Kranken-Anstalt gGmbH, Bochum-Mitte /ID# 224695

    Bochum, North Rhine-Westphalia, 44791, Germany

  • Azienda Ospedaliera Universitaria Federico II /ID# 224673

    Naples, Napoli, 80131, Italy

  • Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone /ID# 221078

    Palermo, 90127, Italy

  • Azienda Ospedaliero Universitaria Careggi /ID# 219090

    Florence, Firenze, 50134, Italy

  • Azienda Ospedaliero Universitaria delle Marche /ID# 238438

    Ancona, 60020, Italy

  • Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 225731

    Rome, Roma, 00161, Italy

  • Azienda ULSS 8 Berica /ID# 221079

    Vicenza, 36100, Italy

  • BAG Freiberg-Richter, Jacobasch, Illmer, Wolf /ID# 221346

    Dresden, Saxony, 01307, Germany

  • Border Medical Oncology Research Unit Albury Wodonga Regiona /ID# 223848

    East Albury, New South Wales, 2640, Australia

  • CHU NIMES - Hopital Caremeau /ID# 219128

    Nîmes, Gard, 30029, France

  • CHU de Nantes, Hotel Dieu -HME /ID# 219127

    Nantes, Pays de la Loire Region, 44000, France

  • CHUQ- Hôpital de l'Enfant-Jesus /ID# 220888

    Québec, Quebec, G1J 1Z4, Canada

  • CISSS-CA (Centre Integre de sante et de services sociaux de Chaudiere-Appalache) /ID# 222433

    Lévis, Quebec, G6V 3Z1, Canada

  • Calvary Mater Newcastle /ID# 224324

    Waratah, New South Wales, 2298, Australia

  • Centre Hospitalier Métropole Savoie - Site Hôpital de Chambéry /ID# 223771

    Chambéry, Savoie, 73007, France

  • Centre Hospitalier Universitaire de Bordeaux /ID# 222696

    Pessac, Gironde, 33604, France

  • Chi Mei Hospital - Liouying /ID# 221144

    Tainan, Tainan, 73657, Taiwan

  • Chiba University Hospital /ID# 224546

    Chiba, Chiba, 260-8677, Japan

  • China Medical University Hospital /ID# 218979

    Taichung, 40447, Taiwan

  • Chu Angers /Id# 219129

    Angers, 49933, France

  • City of Hope /ID# 218996

    Duarte, California, 91010, United States

  • Clin Hosp Ctr Bezanijska Kosa /ID# 231059

    Belgrade, Beograd, 11080, Serbia

  • Clinic UZI 4D /ID# 221303

    Pyatigorsk, Stavropol Kray, 357502, Russia

  • Clinical Hospital Dubrava /ID# 230801

    Zagreb, City of Zagreb, 10000, Croatia

  • Cliniques Universitaires UCL Saint-Luc /ID# 224221

    Brussels, Brussels Capital, 1200, Belgium

  • Columbus Regional Research Institute /ID# 224410

    Columbus, Georgia, 31904-8915, United States

  • Complejo Hospitalario Universitario A Coruña /ID# 224617

    A Coruña, A Coruna, 15006, Spain

  • Dana-Farber Cancer Institute /ID# 218998

    Boston, Massachusetts, 02215, United States

  • Debreceni Egyetem-Klinikai Kozpont /ID# 220947

    Debrecen, Hajdú-Bihar, 4032, Hungary

  • Dokkyo Medical University Saitama Medical Center /ID# 222334

    Koshigaya, Saitama, 343-0845, Japan

  • Dup_Guys and St Thomas NHS Foundation Trust - Guy's Hospital /ID# 221041

    London, Greater London, SE1 9RT, United Kingdom

  • Duplicate_Assuta Ashdod Medical Center /ID# 225281

    Ashdod, Southern District, 7747629, Israel

  • Duplicate_CHU DE NICE-HOPITAL LARCHET II /ID# 256291

    Nice, Alpes-Maritimes, 06200, France

  • Duplicate_Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Universita /ID# 219087

    Rome, Lazio, 00168, Italy

  • Duplicate_Hospital Clínico Universitario de Santiago-CHUS /ID# 221616

    Santiago de Compostela, A Coruna, 15706, Spain

  • Duplicate_Houston Methodist Hospital /ID# 223103

    Houston, Texas, 77030, United States

  • Duplicate_IRCCS AOU di Bologna - Policlinico Sant'Orsola-Malpighi /ID# 221077

    Bologna, Emilia-Romagna, 40138, Italy

  • Duplicate_Ochsner Clinic Foundation-New Orleans /ID# 222777

    New Orleans, Louisiana, 70121, United States

  • Duplicate_University Hospital Santa Maria della Misericordia /ID# 221241

    Udine, 33100, Italy

  • Duplicate_Universitätsspital Basel /ID# 221261

    Basel, Canton of Basel-City, 4031, Switzerland

  • Duplicate_Wits Clinical Research Site /ID# 231554

    Johannesburg, Gauteng, 2193, South Africa

  • Ege University Medical Faculty /ID# 224570

    Izmir, 35040, Turkey (Türkiye)

  • Ehime University Hospital /ID# 221158

    Toon-shi, Ehime, 791-0295, Japan

  • Fakultní Nemocnice Brno - Jihlavská /ID# 220959

    Brno, Brno-mesto, 625 00, Czechia

  • Fejér Vármegyei Szent György Egyetemi Oktató Kórház /ID# 220949

    Székesfehérvár, Fejér, 8000, Hungary

  • Feofaniya Clinical Hospital of State Management of Affairs /ID# 271397

    Kyiv, 03143, Ukraine

  • Fondazione IRCCS San Gerardo dei Tintori - Ospedale San Gerardo /ID# 225113

    Monza, Monza E Brianza, 20052, Italy

  • Fox Chase Cancer Center /ID# 223955

    Philadelphia, Pennsylvania, 19111, United States

  • Fujita Health University Hospital /ID# 221598

    Toyoake, Aichi-ken, 470-1192, Japan

  • Fukushima Medical University Hospital /ID# 221877

    Fukushima, Fukushima, 960-1295, Japan

  • Gachon University Gil Medical Center /ID# 220972

    Incheon, Gyeonggido, 21565, South Korea

  • Galilee Medical Center /ID# 225280

    Nahariya, Northern District, 2210001, Israel

  • Gemeinschaftspraxis Dr. Heinrich und Prof. Bangerter /ID# 225025

    Augsburg, Bavaria, 86150, Germany

  • General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 221179

    Athens, 10676, Greece

  • General Hospital of Athens Laiko /ID# 221175

    Athens, Attica, 11527, Greece

  • General Hospital of Thessaloniki George Papanikolaou /ID# 221463

    Thessaloniki, 57010, Greece

  • Gifu University Hospital /ID# 224371

    Gifu, Gifu, 501-1194, Japan

  • Grand Hôpital de Charleroi - Les Viviers /ID# 224827

    Charleroi, Hainaut, 6280, Belgium

  • Grande Ospedale Metropolitano Bianchi - Melacrino - Morelli P.O. Riuniti /ID# 221220

    Reggio Calabria, 89125, Italy

  • Gulhane Askeri Tip Academy /ID# 224568

    Ankara, 06010, Turkey (Türkiye)

  • HCL - Hopital Lyon Sud /ID# 222695

    Pierre-Bénite, Rhone, 69495, France

  • HSHS St. Vincent Hospital /ID# 224468

    Green Bay, Wisconsin, 54301, United States

  • HaEmek Medical Center /ID# 220839

    Afula, H_efa, 1834111, Israel

  • Hacettepe Universitesi Hastaneleri /ID# 271084

    Ankara, 06230, Turkey (Türkiye)

  • Hackensack Univ Med Ctr /ID# 219047

    Hackensack, New Jersey, 07601, United States

  • Hadassah Medical Center-Hebrew University /ID# 219111

    Jerusalem, Jerusalem, 91120, Israel

  • Hadassah Mt. Scopus /ID# 253394

    Jerusalem, Jerusalem, 9765400, Israel

  • Hanusch Krankenhaus /ID# 220912

    Vienna, 1140, Austria

  • Henry Ford Hospital /ID# 221190

    Detroit, Michigan, 48202, United States

  • Highlands Oncology Group, PA /ID# 221826

    Springdale, Arkansas, 72762, United States

  • Hopital Avicenne - APHP /ID# 221287

    Bobigny, Île-de-France Region, 93000, France

  • Hospital Clinico Universitario de Valencia /ID# 220920

    Valencia, 46010, Spain

  • Hospital Parc de Salut del Mar /ID# 220922

    Barcelona, 08003, Spain

  • Hospital Regional Universitario de Malaga /ID# 221906

    Málaga, 29011, Spain

  • Hospital Universitario 12 de Octubre /ID# 233726

    Madrid, 28041, Spain

  • Hospital Universitario Central de Asturias /ID# 224815

    Oviedo, Principality of Asturias, 33011, Spain

  • Hospital Universitario Dr. Negrin /ID# 220923

    Las Palmas de Gran Canaria, Las Palmas, 35019, Spain

  • Hospital Universitario Germans Trias i Pujol /ID# 233727

    Badalona, Barcelona, 08916, Spain

  • Hospital Universitario La Paz /ID# 224813

    Madrid, 28046, Spain

  • Hospital Universitario Vall d'Hebron /ID# 240979

    Barcelona, 08035, Spain

  • Hospital Universitario Virgen de las Nieves /ID# 253936

    Granada, 18014, Spain

  • Hospital Universitario Virgen del Rocio /ID# 221932

    Seville, 41013, Spain

  • Hospital Universitario de Salamanca /ID# 221904

    Salamanca, 37711, Spain

  • Hospital del Centro Comprensivo de Cancer de la UPR /ID# 223281

    San Juan, 00927, Puerto Rico

  • Hospital n.a. V.V. Veresaev /ID# 225221

    Moscow, 127644, Russia

  • Hospital of the University of Pennsylvania /ID# 219001

    Philadelphia, Pennsylvania, 19104-4238, United States

  • Hôpital Saint-Louis /ID# 221390

    Paris, 75010, France

  • IMSUT Hospital, The Institute of Medical Science, The University of Tokyo /ID# 257944

    Tokyo, 108-8639, Japan

  • Icri /Id# 221967

    Whittier, California, 90603, United States

  • Indiana Blood & Marrow Transpl /ID# 221587

    Indianapolis, Indiana, 46237, United States

  • Inselspital, Universitaetsspital Bern /ID# 223439

    Bern, 3010, Switzerland

  • Ironwood Cancer & Res Ctr /ID# 222162

    Chandler, Arizona, 85224-5665, United States

  • Iwate Medical University Hospital /ID# 222044

    Shiwa-gun, Iwate, 028-3695, Japan

  • James Paget University Hospitals NHS Foundation Trust /ID# 221219

    Great Yarmouth, Norfolk, NR31 6LA, United Kingdom

  • Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital /ID# 221150

    Nagoya, Aichi-ken, 453-8511, Japan

  • Juntendo University Hospital /ID# 221154

    Bunkyo-ku, Tokyo, 113-8431, Japan

  • Juntendo University Shizuoka Hospital /ID# 221780

    Izunokuni-shi, Shizuoka, 410-2295, Japan

  • Juravinski Cancer Centre /ID# 220887

    Hamilton, Ontario, L8V 1C3, Canada

  • Kanazawa University Hospital /ID# 223028

    Kanazawa, Ishikawa-ken, 920-8641, Japan

  • Kansai Medical University Hospital /ID# 257289

    Hirakata-shi, Osaka, 573-1191, Japan

  • Kaohsiung Chang Gung Memorial Hospital /ID# 218985

    Kaohsiung City, Kaohsiung, 833, Taiwan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 218980

    Kaohsiung City, 807, Taiwan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 271389

    Kaohsiung City, 807, Taiwan

  • Klinicka bolnica Merkur /ID# 230799

    Zagreb, City of Zagreb, 10000, Croatia

  • Klinicki Bolnicki Centar (KBC) Split /ID# 230800

    Split, Split-Dalmatia County, 21000, Croatia

  • Klinicki bolnicki centar Osijek /ID# 231503

    Osijek, County of Osijek-Baranja, 31000, Croatia

  • Klinicki bolnicki centar Zagreb /ID# 230798

    Zagreb, City of Zagreb, 10000, Croatia

  • Klinikum Chemnitz gGmbH /ID# 224575

    Chemnitz, Saxony, 09116, Germany

  • Klinikum Wels-Grieskirchen GmbH /ID# 220915

    Wels, Upper Austria, 4600, Austria

  • Klinikum rechts der Isar /ID# 221526

    Munich, 81675, Germany

  • Kobe City Medical Center General Hospital /ID# 221156

    Kobe, Hyōgo, 650-0047, Japan

  • Kumamoto Shinto General Hospital /ID# 255645

    Kumamoto, Kumamoto, 862-8655, Japan

  • Kurashiki Central Hospital /ID# 221690

    Kurashiki-shi, Okayama-ken, 710-8602, Japan

  • Kyoto University Hospital /ID# 223008

    Kyoto, Kyoto, 606-8507, Japan

  • Kyushu University Hospital /ID# 221606

    Fukuoka, Fukuoka, 812-8582, Japan

  • Linkou Chang Gung Memorial Hospital /ID# 218982

    Taoyuan City, 333, Taiwan

  • Long Beach Memorial Medical Ct /ID# 224542

    Long Beach, California, 90806-1701, United States

  • Loyola University Medical Ctr /ID# 219048

    Maywood, Illinois, 60153, United States

  • Lux Med Onkologia - Szpital Szamocka /Id# 221265

    Warsaw, Masovian Voivodeship, 01-748, Poland

  • MTZ Clinical Research Powered by Pratia /ID# 221759

    Warsaw, Masovian Voivodeship, 02-172, Poland

  • Manhattan Hematology Oncology MHO Associates /ID# 223193

    New York, New York, 10016-6028, United States

  • McGill University Health Centre - Glen Site /ID# 222614

    Montreal, Quebec, H4A 3J1, Canada

  • Medipol Mega Üniversite Hastanesi /ID# 271374

    Tuzla, Istanbul, 34953, Turkey (Türkiye)

  • Medizinische Universitaet Graz /ID# 220919

    Graz, Styria, 8010, Austria

  • Medizinische Universitaet Wien /ID# 220911

    Vienna, State of Vienna, 1090, Austria

  • Memorial Sloan Kettering Cancer Center-Koch Center /ID# 221081

    New York, New York, 10065-6007, United States

  • Mersin University Medical /ID# 224571

    Mersin, 33343, Turkey (Türkiye)

  • MetroHealth Medical Center /ID# 222650

    Cleveland, Ohio, 44109, United States

  • Mie University Hospital /ID# 221665

    Tsu, Mie-ken, 514-8507, Japan

  • Moores Cancer Center /ID# 271596

    La Jolla, California, 92037, United States

  • Moores Cancer Center at UC San Diego /ID# 219009

    La Jolla, California, 92093, United States

  • Moscow State budget healthcare /ID# 221116

    Moscow, Moscow, 125284, Russia

  • NHS Lothian /ID# 224378

    Edinburgh, EH3 9HE, United Kingdom

  • National Cancer Center Hospital East /ID# 226653

    Kashiwa-shi, Chiba, 277-8577, Japan

  • National Cheng Kung University Hospital /ID# 271206

    Tainan, 704, Taiwan

  • National Taiwan University Hospital /ID# 271207

    Taipei City, Taipei, 100, Taiwan

  • Niigata University Medical & Dental Hospital /ID# 223034

    Niigata, Niigata, 951-8520, Japan

  • Nippon Medical School Hospital /ID# 221676

    Bunkyo-ku, Tokyo, 113-8602, Japan

  • Northwest Oncology & Hematology - Elk Grove Village /ID# 222818

    Elk Grove Village, Illinois, 60007-3361, United States

  • Olympion General Clinic /ID# 261423

    Pátrai, Achaia, 25443, Greece

  • OncoResearch Lerchenfeld GmbH /ID# 225034

    Hamburg, 22081, Germany

  • Ondokuz mayis University Facul /ID# 224567

    Samsun, 55200, Turkey (Türkiye)

  • Ordensklinikum Linz GmbH Elisabethinen /ID# 220914

    Linz, Upper Austria, 4010, Austria

  • Ottawa Hospital Research Institute /ID# 238858

    Ottawa, Ontario, K1H 8L6, Canada

  • Pennsylvania Cancer Specialists & Research Institute /ID# 271376

    Gettysburg, Pennsylvania, 17325, United States

  • Pratia Onkologia Katowice /ID# 224526

    Katowice, 40-519, Poland

  • Providence - St. Jude Medical Center /ID# 271382

    Fullerton, California, 92835, United States

  • Providence Everett /ID# 223130

    Everett, Washington, 98201, United States

  • Pusan National University Hospital /ID# 220980

    Busan, Busan Gwang Yeogsi, 49241, South Korea

  • Rabin Medical Center /ID# 219139

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus /ID# 219121

    Haifa, H_efa, 3109601, Israel

  • Roskilde Sygehus /ID# 224456

    Roskilde, Region Sjælland, 4000, Denmark

  • Royal Perth Hospital /ID# 221099

    Perth, Western Australia, 6000, Australia

  • Russian Research Institute of Hematology and Transfusiology of the FMBA /ID# 221115

    Saint Petersburg, 191024, Russia

  • SP ZOZ Szpital Uniwersytecki w Krakowie /ID# 221160

    Krakow, Lesser Poland Voivodeship, 31-501, Poland

  • Saint Louis University Cancer Center /ID# 222287

    St Louis, Missouri, 63110-2539, United States

  • Samsung Medical Center /ID# 221091

    Seoul, Seoul Teugbyeolsi, 06351, South Korea

  • Sapporo Hokuyu Hospital /ID# 221149

    Sapporo, Hokkaido, 003-0006, Japan

  • Seoul National University Hospital /ID# 219060

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • Shonan Kamakura General Hospital /ID# 223030

    Kamakura-shi, Kanagawa, 247-8533, Japan

  • Skane University Hospital Lund /ID# 220834

    Lund, Skåne County, 224 84, Sweden

  • Somogy Varmegyei Kaposi Mor Oktato Korhaz /ID# 220948

    Kaposvár, Somogy County, 7400, Hungary

  • St. Mary's Hospital Regional Cancer Center /ID# 224229

    Grand Junction, Colorado, 81501-6132, United States

  • Stauferklinikum Schwaebisch Gmuend /ID# 223948

    Mutlangen, Baden-Wurttemberg, 73557, Germany

  • Summit Medical Group-Florham Park /ID# 222620

    Florham Park, New Jersey, 07932-1049, United States

  • Szabolcs-Szatmar-Bereg Varmegyei Oktatokorhaz /ID# 220946

    Nyíregyháza, Szabolcs-Szatmár-Bereg, 4400, Hungary

  • Szegedi Tudományegyetem /ID# 220955

    Szeged, 6720, Hungary

  • Szpital Kliniczny im. Heliodora Swiecickiego Uniwersytetu Medycznego im. Karola /ID# 241031

    Poznan, Greater Poland Voivodeship, 60-569, Poland

  • Taipei Veterans General Hosp /ID# 221147

    Taipei, 11217, Taiwan

  • Tel Aviv Sourasky Medical Center /ID# 219135

    Tel Aviv, Tel Aviv, 6423906, Israel

  • Texas Oncology - Abilene - Antilley Road /ID# 271379

    Abilene, Texas, 79606, United States

  • The Alfred Hospital /ID# 221096

    Melbourne, Victoria, 3004, Australia

  • The Cancer Institute at St. Francis Hospital /ID# 231782

    Greenvale, New York, 11548-1219, United States

  • The Catholic University of Korea, Seoul St. Marys Hospital /ID# 219061

    Seoul, Seoul Teugbyeolsi, 06591, South Korea

  • The Chaim Sheba Medical Center /ID# 219136

    Ramat Gan, Tel Aviv, 5265601, Israel

  • The Kinghorn Cancer Centre /ID# 221097

    Darlinghurst, New South Wales, 2010, Australia

  • The Lady Davis Carmel Medical Center /ID# 222973

    Haifa, H_efa, 34362, Israel

  • The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 221335

    Newcastle upon Tyne, NE3 3HD, United Kingdom

  • The University of Osaka Hospital /ID# 221159

    Suita-shi, Osaka, 565-0871, Japan

  • Tokyo Medical University Hospital /ID# 221540

    Shinjuku-ku, Tokyo, 160-0023, Japan

  • Tokyo Metropolitan Bokutoh Hospital /ID# 254774

    Sumida-ku, Tokyo, 130-8575, Japan

  • Trakya University Medical Facu /ID# 224572

    Edirne, Istanbul, 22030, Turkey (Türkiye)

  • Tula Regional Clinical Hospital /ID# 221302

    Tula, 300053, Russia

  • Tulane Medical Center - New Orleans /ID# 222940

    New Orleans, Louisiana, 70112-2600, United States

  • UMHAT Alexandrovska EAD /ID# 231652

    Sofiya, Sofia, 1431, Bulgaria

  • UMHAT Dr Georgi Stranski EAD /ID# 231650

    Pleven, 5800, Bulgaria

  • UMHAT Sveta Marina /ID# 234119

    Varna, 9010, Bulgaria

  • UMHAT Sveti Ivan Rilski /ID# 231651

    Sofia, 1431, Bulgaria

  • UZ Gent /ID# 220841

    Ghent, Oost-Vlaanderen, 9000, Belgium

  • United Lincolnshire Hospitals NHS Trust /ID# 224613

    Lincoln, Lincolnshire, LN2 4AX, United Kingdom

  • Universitaetsklinikum St. Poelten /ID# 221709

    Sankt Pölten, Lower Austria, 3100, Austria

  • Universitaetsmedizin Rostock /ID# 224157

    Rostock, Mecklenburg-Vorpommern, 18057, Germany

  • Universitatsklinikum Mannheim /ID# 221529

    Mannheim, Baden-Wurttemberg, 68167, Germany

  • University Clinical Center Serbia /ID# 231058

    Belgrade, Beograd, 11000, Serbia

  • University Clinical Center Vojvodina /ID# 231057

    Novi Sad, 21000, Serbia

  • University General Hospital of Patras /ID# 221178

    RION Patras Achaia, 26504, Greece

  • University Health Network_Princess Margaret Cancer Centre /ID# 253942

    Toronto, Ontario, M5G 2M9, Canada

  • University Hospitals Birmingham NHS Foundation Trust /ID# 221334

    Birmingham, B15 2TH, United Kingdom

  • University of Chicago Medical Center /ID# 271373

    Chicago, Illinois, 60637, United States

  • University of Michigan /ID# 218463

    Ann Arbor, Michigan, 48109, United States

  • University of Miyazaki Hospital /ID# 221821

    Miyazaki, Miyazaki, 889-1692, Japan

  • University of Texas Health San Antonio MD Anderson Cancer Center /ID# 233942

    San Antonio, Texas, 78229, United States

  • University of Yamanashi Hospital /ID# 221706

    Chuo-shi, Yamanashi, 409-3821, Japan

  • Uniwersytecki Szpital Kliniczny Nr 1 w Lublinie /ID# 221124

    Lublin, Lublin Voivodeship, 20-081, Poland

  • Uniwersyteckie Centrum Kliniczne /ID# 221298

    Gdansk, Pomeranian Voivodeship, 80-214, Poland

  • Utah Cancer Specialists Salt Lake Clinic /ID# 221962

    Salt Lake City, Utah, 84106, United States

  • Virginia Cancer Specialists - Fairfax /ID# 223016

    Fairfax, Virginia, 22031, United States

  • Vitaz /Id# 228150

    Sint-Niklaas, Oost-Vlaanderen, 9100, Belgium

  • Vseobecna fakultni nemocnice v Praze /ID# 220969

    Prague, 128 08, Czechia

  • William Beaumont Hospital /ID# 222705

    Royal Oak, Michigan, 48073-6710, United States

  • Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopern /ID# 221161

    Lodz, Łódź Voivodeship, 93-513, Poland

  • Yakima Valley Memorial Hosp /ID# 224368

    Yakima, Washington, 98902-6388, United States

  • Yitzhak Shamir Medical Center /ID# 222972

    Ẕerifin, Central District, 70300, Israel

  • ZAS Cadix /ID# 221468

    Antwerp, Antwerpen, 2030, Belgium

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