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New drug ZE74-0282 targets rare blood cancers in early trial

NCT ID NCT07529951

First seen Apr 23, 2026 · Last updated May 23, 2026 · Updated 4 times

Summary

This early-phase study tests an experimental drug, ZE74-0282, in about 60 adults with polycythemia vera or myelofibrosis caused by a JAK2 V617F mutation. The main goals are to find the safest dose and see if the drug shows signs of fighting the disease. Participants will take the drug by mouth, and doctors will monitor side effects and blood changes closely.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Conditions

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