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Nose shape linked to allergies in kids?

NCT ID NCT06139185

Knowledge-focused Sponsor: Federico II University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study examined 69 children aged 6 to 14 to see if a deviated nasal septum (a crooked wall inside the nose) is linked to allergic rhinitis (hay fever). Researchers compared kids with and without the deviation using allergy tests, nasal samples, and quality-of-life questionnaires. The goal was to understand if this common anatomical variation increases the risk of developing allergies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study finds a link, it could help doctors identify children at higher risk for allergic rhinitis and guide earlier diagnosis or treatment.
What could go wrong
This is a small, completed observational study, not a treatment trial. It only shows association, not cause, and results may not apply to non-Caucasian children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

69 people

The number who actually took part.

Started

Jan 2023

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Caucasian children of both sexes aged between 6 and 14 with and without suspected deviation of the nasal septum observed at Pediatrics Section of Department of Translational Medical Sciences (University of Naples Federico II), University of Calabria (Department of Pharmacy, Health and Nutrition Sciences) and Otorhinolaryngology Unit, Penne Hospital, ASL of Pescara

Ages

6 to 14 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Caucasian ethnicity * both sexes * age between 6 and 14 years * written informed consent. Exclusion Criteria: * Non-Caucasian ethnicity * Age \<6 and \>14 years Concomitant presence of: * chronic diseases * malignancies * immunodeficiency * chronic infections * autoimmune diseases * chronic inflammatory intestinal diseases * celiac disease * genetic diseases * metabolic diseases * cystic fibrosis * chronic pulmonary diseases * malformations of the cardiovascular system * malformations of the respiratory system * malformations of the gastrointestinal system * neuropsychiatric disorders * neurological diseases * obesity * eosinophilic diseases * antibiotics use in the last 7 days * cortisone use in the last 7 days * antihistamines use in the last 7 days * trauma at nose level in the 3 years before the enrollment, * history of previous nose surgery, or previous major surgery procedures of gastrointestinal, cardiovascular, urinary or respiratory tract

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Conditions

The condition(s) this trial relates to.

allergic rhinitis Rhinitis, Allergic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Rhinitis allergic

Contacts and locations

Locations

  • Department of Traslational Medical Science - University of Naples Federico II

    Naples, 80131, Italy

  • University of Naples Federico II

    Naples, Italy

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