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Power nap power: can a short snooze boost brain recovery after stroke?

NCT ID NCT04312126

Knowledge-focused Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 19, 2026 · Updated 5 times

Summary

This study looks at how taking a nap helps the brain remember new motor skills, like typing a sequence. Researchers will use brain scans to see what happens during rest and sleep. The study includes adults who have had a stroke and healthy volunteers of different ages. The goal is to understand memory replay and how it supports learning.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 199 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2021

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Right-handed adults between the ages of 18 and 80.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* HEALTHY VOLUNTEERS: INCLUSION CRITERIA: * Age 18-35 (Arm 1) or 50-80 (Arms 2). * English speaking. * Clear right-hand dominance (\>74 on Edinburgh Handedness Inventory). * Normal neurological examination as determined by the screening clinician. EXCLUSION CRITERIA: * HCPS affiliated NIH staff (i.e. - staff from our section). * Current pregnancy. * Contraindications for MRI or MEG. * Use of sleep medications within 24 hours of Experimental Session participation. * Severe or progressive neurological, psychological or medical condition as determined by the screening clinician. STROKE PATIENTS: INCLUSION CRITERIA: * Age 18 or older * Willing and able to provide consent * Experienced a stroke 6 months ago or more that affected at least one of the upper extremities at time of stroke diagnosis * Ability to perform the study task as assessed during physical examination * English-speaking EXCLUSION CRITERIA: * HCPS-affiliated NIH staff (i.e. - staff from our section). * Current pregnancy * History of large stroke lesions in brainstem or cerebellum as determined by screening clinician * Severe or progressive neurological disorder other than stroke (e.g., Parkinson s disease or multiple sclerosis) as determined by the screening clinician * Uncontrolled heart, lung, kidney, gastrointestinal, metabolic, psychiatric, sleep, or endocrine disorders as determined by the screening clinician * Contraindications for MRI or MEG.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.