New DNA scanner could speed up diagnosis of eye infections
NCT ID NCT05372861
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study is testing whether a portable DNA sequencing device (Oxford Nanopore MinION) can quickly and accurately identify the bacteria or fungi causing endophthalmitis, a severe eye infection. Researchers will compare the new method's results and speed against standard lab cultures. The study involves 20 patients with endophthalmitis who are having vitrectomy surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Nanopore sequencing (Oxford Nanopore MinION device)
- What this could lead to
- If successful, this method could provide faster and more accurate identification of the germs causing serious eye infections, helping doctors choose the right treatment sooner.
- What could go wrong
- This is a very small pilot study with only 20 participants, so results may not apply to all patients. The new sequencing method may not prove more reliable than standard lab cultures.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2022
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Eyes of adult patients with endophthalmitis
- Ages
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18 to 99 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Eyes of patients with endophthalmitis Exclusion Criteria: * No informed consent possible * Participation in other studies
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Universitäts Augenklinik Graz
RECRUITINGGraz, Styria, 8036, Austria
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