Nalbuphine vs morphine: which painkiller wins for Post-Surgery relief?
NCT ID NCT03288428
First seen May 22, 2026 · Last updated Jun 22, 2026 · Updated 9 times
Summary
This study compared two painkillers, nalbuphine and morphine, given through a patient-controlled pump to 80 women recovering from laparoscopic myomectomy (surgery to remove uterine fibroids). The goal was to see which one provides better pain relief and causes fewer side effects. Participants rated their pain on a 1-10 scale, and the results help doctors choose the best option for post-surgery comfort.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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First hospital Peking University
Beijing, Beijing Municipality, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nalbuphine and morphine (painkillers given through a patient-controlled pump)
What this could lead to
If nalbuphine works as well as morphine with fewer side effects, it could become a preferred option for managing pain after this surgery.
What could go wrong
This is a small, completed phase 4 trial with only 80 participants, so results may not apply to everyone. Differences between the drugs may be small or not meaningful.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.