Could this antioxidant supercharge your workout results?
NCT ID NCT07196852
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether taking N-acetylcysteine (NAC), an antioxidant supplement, can improve the health and fitness benefits of high-intensity interval training in adults with overweight or obesity. Researchers will measure changes in body composition, fitness, and blood markers of inflammation and oxidative stress. The goal is to see if NAC can help the body respond better to exercise, potentially making workouts more effective for improving metabolic health.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * BMI 25-35 kg/m2 * Free of musculoskeletal injuries * Free of chronic non-communicable diseases * Do not receive any drug therapy * Do not receive dietary supplements * Normal menstrual cycle (for females) * Non smokers Exclusion Criteria: * NAC intolerance * Bleeding disorders * Kidney disease * Asthma * Usage of blood thinners and/or angina medication
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Physical Education and Sport Science, University of Thessaly
RECRUITINGTrikala, Karies, 42100, Greece
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