Antioxidant showdown: can N-Acetylcysteine or Alpha-Lipoic acid shield kidneys from colistin?
NCT ID NCT06650384
First seen Feb 28, 2026 · Last updated Apr 30, 2026 · Updated 9 times
Summary
This study tested two antioxidants, N-Acetylcysteine and Alpha-Lipoic acid, to see if they could prevent kidney damage caused by the strong antibiotic colistin in 180 critically ill ICU patients. Patients received one of the antioxidants alongside colistin, and researchers monitored kidney function daily. The goal was to find a safe way to reduce the need for dialysis or dose changes.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Critical Care Medicine Department,Cairo University Hospitals
Cairo, Egypt
Conditions
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