Could a common antidote help stroke patients?
NCT ID NCT04918719
First seen Feb 19, 2026 · Last updated Jun 23, 2026 · Updated 26 times
Summary
This study tested whether giving N-Acetylcysteine (NAC) intravenously soon after an acute ischemic stroke could improve outcomes. Only 4 adults with moderate to severe stroke were enrolled. Researchers measured stroke severity and disability at 30 and 90 days. The trial is complete, but the tiny size means results are very preliminary.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
-
Harbor-UCLA Medical Center
Torrance, California, 90502, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
N-Acetylcysteine (NAC)
What this could lead to
If it works, this could point toward a new treatment to reduce brain damage and improve recovery after a stroke.
What could go wrong
This was a very small early-phase trial with only 4 participants, so results may not apply broadly. NAC is not yet proven effective for stroke.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.