Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Muscle clues: simple protein test may forecast hospital stay in inflammation patients

NCT ID NCT07476391

Knowledge-focused Sponsor: Charles University, Czech Republic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explored whether levels of two muscle proteins, myostatin and irisin, can help predict how long patients with systemic inflammation (SIRS) will stay in the hospital. Researchers observed 54 adults admitted with acute illness and signs of SIRS, measuring these proteins and tracking their recovery. The goal was to see if these muscle signals could serve as early warning signs for longer hospital stays and muscle problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

54 people

The number who actually took part.

Started

Apr 2023

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Study group consisted of patients admitted to General University Hospital in Prague with acute illness fulfilling the inclusion criteria. Healthy controls consisted of healthy volunteers free of acute or chronic illnesses that could confound study outcomes (any autoimmune, inflammatory, cardiovascular, metabolic, or other systemic disease requiring treatment).

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Hospital admission with acute illness * Presence of systemic inflammatory response syndrome (SIRS) defined by at least two of the following: body temperature \>38°C or \<36°C heart rate \>90 bpm respiratory rate \>20/min or PaCO₂ \<4.3 kPa leukocytosis \>12 × 10⁹/L or leukopenia \<4 × 10⁹/L * Expected hospital stay ≥5 days * Ability to provide informed consent Exclusion Criteria: * Transfer from another hospital with prior hospitalization \>48 hours * Terminal illness (malignant or non-malignant) * Long-term immobility prior to hospital admission * Conditions preventing participation in study procedures

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Systemic inflammatory response syndrome (SIRS) are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Critical Illness Systemic Inflammatory Response Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Systemic inflammatory response syndrome (SIRS)

Contacts and locations

Locations

  • General University Hospital in Prague

    Prague, 12000, Czechia

More trials for these conditions

Other studies related to the condition(s) this trial covers.