Charles University, Czech Republic

This study tests a new automated insulin delivery system (the Medtrum TouchCare Nano with APGO algorithm) in 200 adults with type 1 diabetes. The system automatically adjusts insulin based on blood sugar levels, aiming to keep glucose in a healthy range. Researchers will measure …

This study looks at how well and how safely a new catheter (Varipulse) can treat a type of irregular heartbeat called non-paroxysmal atrial fibrillation. About 50 adults will get the procedure, which uses energy to create small scars in the heart to block faulty signals. Research…

This study compares a newer surgical method (transobturator cystocele repair) with the standard native tissue repair for fixing a bladder prolapse (cystocele) in women aged 50 and older. About 592 participants will be followed to see which approach better corrects the prolapse an…

This study tests whether a program of physical activity, nutritional advice, and psychological support before surgery can improve recovery and quality of life in patients with ovarian or endometrial cancer. 64 participants will be randomly assigned to either receive standard care…

This study tests if using magnetic brain stimulation right before electroconvulsive therapy (ECT) can make ECT work better for people with hard-to-treat depression. About 50 adults with severe depression will receive both treatments, and researchers will measure changes in seizur…

This study looks at whether military medics with little intubation experience can safely use the SaCoVLM™ video laryngeal mask airway. It has two parts: training on a simulator and then using the device on sedated patients having elective surgery. The goal is to see how often the…

This study looks at why many people with COPD and asthma do not use their inhalers correctly, and tests new ways to help them stick to their treatment. Researchers will work with 1,000 patients and their healthcare providers to measure adherence and improve inhalation techniques …

This study looks back at breast milk donations made to a hospital milk bank over five years. Researchers will check how much milk was donated and what factors like the mother's age, weight, and delivery method affect the milk's quality. The goal is to learn more about donor milk,…

This study follows 209 children and adults hospitalized with tick-borne encephalitis (TBE) in the Czech Republic for one year after they leave the hospital. Researchers check on participants at several points to see which symptoms like tiredness, headaches, or memory problems las…

This study looks at how a new procedure called pulse field ablation affects the heart's upper chambers in people with a type of irregular heartbeat called paroxysmal atrial fibrillation. Researchers will measure changes in heart function using ultrasound during the procedure. The…