Can special glasses stop Kids' eyesight from getting worse?
NCT ID NCT05886348
First seen Jun 24, 2026 · Last updated Sep 18, 2026 · Updated 2 times
Summary
This study tests whether new spectacle lenses can safely slow the progression of myopia (nearsightedness) in children. About 249 kids will wear either the novel lenses or standard single vision glasses for 36 months. Researchers will measure changes in eye length and prescription strength to see if the new lenses work better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Novel spectacle lenses (Model-A and Model-B)
- What this could lead to
- If successful, these lenses could offer a non-invasive way to slow down worsening nearsightedness in children, reducing the need for stronger prescriptions.
- What could go wrong
- This is a mid-sized trial, and results may not apply to all children. The lenses might not slow myopia better than standard glasses, and long-term effects are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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249 people
The number who actually took part.
- Started
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Jul 2023
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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7 to 13 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Participant and parent (or guardian) are able and willing to provide consent 2. Participant and parent (or guardian) ensure to attend required study visits and adhere to participant requirements 3. Parent or guardian understands and accepts random allocation of grouping, and that participant and parent (or guardian) will not be told which group participant is allocated to 4. Participant willing to wear the study spectacles lens for a minimum of 12 hours per day for the duration of the study 5. Age at time of parent or guardian consent and participant assent: 7 - 13 years old 6. Spherical equivalent cycloplegic autorefraction: -1.00 to -7.00 D in each eye. 7. Cycloplegic autorefraction astigmatism of 1.50 D or less in each eye 8. Cycloplegic autorefraction anisometropia of 1.50 D or less 9. Monocular best corrected distance visual acuity (BCDVA) equal to or better than logMAR 0.10 in each eye. Exclusion Criteria: 1. Participant is allergy to fluorescein, benoxinate, proparacaine, tropicamide or cyclopentolate eye drops 2. Any ocular and systemic abnormalities might be expected to affect visual functions or refractive development 3. (a) Have received treatment of myopic control pharmaceutical medication (e.g., atropine) or light fundus illuminance therapy (e.g., repeated red light therapy) within 6 months prior to entry into this study. (b) Have received treatment of myopia control such as contact lenses, orthokeratology lenses etc., progressive addition lenses, bifocal lenses, within 3 months. (c) Have received treatment of myopia control such as defocus spectacle lenses (difference between both eye's non-cycloplegic autorefraction and lens-meter results of the respective lenses are equal or less than 0.50 D SER) etc. within one month prior to entry into this study. 4. Participant with clinically significant strabismus (including intermittent tropia) 5. Medical history of binocular vision abnormalities 6. Participant with amblyopia 7. Participation in a clinical trial within 30 days prior to entry into this study or during participation 8. Previous intraocular surgery 9. Participant who, in the judgment of the Investigator, presence of any emotional, physiologic, or anatomical condition which may preclude participation in this study or provide an inappropriate landscape for the intended study treatment. 10. Any medical treatment or medication which might have an influence on vision or interfere with study assessments 11. Pathological myopia (myopia that leads to structural changes in the posterior segment of the eye including posterior staphyloma, myopic maculopathy, and high myopia-associated optic neuropathy)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Beijing Tongren Hospital, Capital Medical University
Beijing, China
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Eye and ENT Hospital of Fudan University
Shanghai, China
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Guangzhou Aier Eye Hospital
Guangzhou, China
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Shengyang He Eye Specialist Hospital
Shengyang, China
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Tianjin Medical University Eye Hospital
Tianjin, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can AI protect Kids' eyesight where eye doctors are scarce?
- Two toric lenses go head to head in vision test
- Eye scans as a window to the body: study probes retinal imaging across diseases
- Lens showdown: which contact lens wins in dim light?
- Myopia glasses may keep working even after kids take them off