New glasses could slow kids' worsening eyesight
NCT ID NCT06927388
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether special open-ring spectacle lenses can slow the progression of nearsightedness (myopia) in Chinese children aged 6 to 12. A total of 180 children will wear one of three lens designs for 12 months, with some continuing for another year. The goal is to see which lens best reduces eye growth and prescription changes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Participants enrolled in the trial must: * be aged between 6 to 12 completed years (6 and 12 years inclusive), irrespective of gender. * For each group, an equal balance of gender will be recruited and 50% of children will be aged between 6- 9 years old and 50% aged 10-12 years old. * be cycloplegic autorefraction spherical component -0.50 D to -4.00D, cylinder no more than -1.50D * be accompanied by parents/guardians who can read and comprehend Chinese and give informed consent as demonstrated by signing a record of informed consent. * be willing to comply with the wearing and clinical trial visit schedule as directed by the Investigator. * have ocular health findings considered to be "normal". * be correctable to at least 6/9.5 (20/30) or better in each eye with spectacles. * be willing to wear the spectacles provided by the investigators for all waking hours. Exclusion Criteria: Participants enrolled in the trial must NOT have: * a known allergy to, or a history of intolerance to tropicamide or topical anaesthetics. * had strabismus and/or amblyopia. * Anisometropia greater than 1.50D spherical equivalent * had previous eye surgery (including strabismus surgery). * any ocular, systemic or other condition or disease with possible associations with myopia or affecting refractive development e.g. Marfan syndrome, retinopathy of prematurity, diabetes. * had any ocular injury or condition (including keratoconus and herpes keratitis) of the cornea, conjunctiva or eyelids. * current orthoptic treatment or vision training. * any anatomical, skin or other condition that would impact on the wearing of spectacles. * Use of or a need for concurrent category S3 and above ocular medication at enrolment and/or during the clinical trial. * Currently enrolled in another clinical trial. * No previous myopia management intervention or treatment within 3 months of enrolment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Xiangui He
Shanghai, 200040, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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