New spectacle lenses aim to halt worsening myopia in children
NCT ID NCT07394556
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether special spectacle lenses can slow the progression of myopia (nearsightedness) in European children aged 6 to 12. A total of 180 kids will wear one of three lens designs for two years. The main goal is to measure changes in eye length and prescription strength over one year.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- myopia control spectacle lenses (Open Ring designs)
- What this could lead to
- If successful, these new lens designs could offer a better option to slow down worsening nearsightedness in children, reducing the need for stronger prescriptions.
- What could go wrong
- This is an early-stage trial with only 180 children, and results may not apply to all kids. The lenses might not slow myopia more than existing options, and long-term effects are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Children aged between 6-12 years old from Spain, Portugal and the United Kingdom
- Ages
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6 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Be aged between 6 to 12 completed years (6 and 12 years inclusive), irrespective of gender. * For each group, an equal balance of gender will be recruited and 50% of children will be aged between 6- 9 years old and 50% aged 10-12 years old. * Be cycloplegic autorefraction spherical component -0.50 D to -6.00D, cylinder no more than -2.00D, and with a spherical equivalent greater than or equal to -6.00D. * Be accompanied by parents/guardians who can read and comprehend give informed consent as demonstrated by signing a record of informed consent. * Be willing to comply with the wearing and clinical trial visit schedule as directed by the Investigator. * Have ocular health findings considered to be "normal". * Be correctable to at least 6/9.5 (20/30) or better in each eye with spectacles. * Be willing to wear the spectacles provided by the investigators for all waking hours. Exclusion Criteria: * A known allergy to, or a history of intolerance to cyclopentolate or topical anesthetics. * Had strabismus and/or amblyopia. * Cylinder more than -2.00D * Anisometropia greater than 1.50D spherical equivalent * Had previous eye surgery (including strabismus surgery). * Any ocular, systemic or other condition or disease with possible associations with myopia or affecting refractive development e.g. Marfan syndrome, retinopathy of prematurity, diabetes. * Had any ocular injury or condition (including keratoconus and herpes keratitis) of the cornea, conjunctiva or eyelids. * Current orthoptic treatment or vision training. * Any anatomical, skin or other condition that would impact on the wearing of spectacles. * Use of or need for concurrent category S3 and above ocular medication at enrolment and/or during the clinical trial. * Currently enrolled in another clinical trial. * No previous myopia management intervention or treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites in 3 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Universitario Clínico San Carlos
Madrid, Spain
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Ulster University
Coleraine, United Kingdom
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Universidade Do Minho
Braga, Portugal
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Special lenses may curb worsening nearsightedness in kids
- Could special glasses stop nearsightedness from getting worse?
- Eye drops could keep Kids' vision from getting worse
- New glasses film aims to stop kids' eyesight from getting worse
- New glasses for nearsighted kids put to the test