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New spectacle lenses aim to halt worsening myopia in children

NCT ID NCT07394556

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether special spectacle lenses can slow the progression of myopia (nearsightedness) in European children aged 6 to 12. A total of 180 kids will wear one of three lens designs for two years. The main goal is to measure changes in eye length and prescription strength over one year.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
myopia control spectacle lenses (Open Ring designs)
What this could lead to
If successful, these new lens designs could offer a better option to slow down worsening nearsightedness in children, reducing the need for stronger prescriptions.
What could go wrong
This is an early-stage trial with only 180 children, and results may not apply to all kids. The lenses might not slow myopia more than existing options, and long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 180 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children aged between 6-12 years old from Spain, Portugal and the United Kingdom

Ages

6 to 12 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be aged between 6 to 12 completed years (6 and 12 years inclusive), irrespective of gender. * For each group, an equal balance of gender will be recruited and 50% of children will be aged between 6- 9 years old and 50% aged 10-12 years old. * Be cycloplegic autorefraction spherical component -0.50 D to -6.00D, cylinder no more than -2.00D, and with a spherical equivalent greater than or equal to -6.00D. * Be accompanied by parents/guardians who can read and comprehend give informed consent as demonstrated by signing a record of informed consent. * Be willing to comply with the wearing and clinical trial visit schedule as directed by the Investigator. * Have ocular health findings considered to be "normal". * Be correctable to at least 6/9.5 (20/30) or better in each eye with spectacles. * Be willing to wear the spectacles provided by the investigators for all waking hours. Exclusion Criteria: * A known allergy to, or a history of intolerance to cyclopentolate or topical anesthetics. * Had strabismus and/or amblyopia. * Cylinder more than -2.00D * Anisometropia greater than 1.50D spherical equivalent * Had previous eye surgery (including strabismus surgery). * Any ocular, systemic or other condition or disease with possible associations with myopia or affecting refractive development e.g. Marfan syndrome, retinopathy of prematurity, diabetes. * Had any ocular injury or condition (including keratoconus and herpes keratitis) of the cornea, conjunctiva or eyelids. * Current orthoptic treatment or vision training. * Any anatomical, skin or other condition that would impact on the wearing of spectacles. * Use of or need for concurrent category S3 and above ocular medication at enrolment and/or during the clinical trial. * Currently enrolled in another clinical trial. * No previous myopia management intervention or treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites in 3 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital Universitario Clínico San Carlos

    Madrid, Spain

  • Ulster University

    Coleraine, United Kingdom

  • Universidade Do Minho

    Braga, Portugal

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