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Can a simple joint glide ease knee arthritis pain?

NCT ID NCT07166068

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 28 times

Summary

This study tests whether a manual therapy called Mobilization with Movement (MWM) can reduce pain and inflammation in people with knee osteoarthritis. Forty adults with moderate to severe knee OA will receive either MWM or a sham treatment twice a week for four weeks, plus standard exercise. Researchers will measure inflammation from blood samples and track pain and function to see if MWM offers real relief.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Jazan University Hospital

    RECRUITING

    Jizan, Jazan Region, 82722, Saudi Arabia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Manual therapy (Mobilization with Movement)

What this could lead to

If it works, this could point toward a non-drug, hands-on treatment option for easing knee osteoarthritis pain and inflammation.

What could go wrong

This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. The sham group also gets exercise, making it hard to isolate MWM's effect.

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.