Mustard gel could replace expensive dental material in Kids' cavities
NCT ID NCT07557290
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares mustard gel, made from black mustard seeds, to a standard dental material (MTA) for treating deep cavities in baby molars. 72 children aged 6-8 will receive one of the two treatments after the damaged nerve is removed. The goal is to see if mustard gel can keep the tooth pain-free and healthy on X-rays for up to 3 months, offering a cheaper and natural alternative.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Mustard gel (from black mustard seeds)
- What this could lead to
- If it works, this could offer a low-cost, natural option for treating deep cavities in baby teeth, reducing the need for expensive materials.
- What could go wrong
- This is a very early Phase 1 trial with only 72 children. Mustard gel may not work as well as MTA, and its safety in this use is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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About 72 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 to 8 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * healthy co-operative children 6-8 years old * primary molars with deep cavities and iatrogenic pulp exposure * clinically with no sign of spontaneous pain, sinus tract, tenderness to percussion, pathological mobility * radiographically with absence of periapical radiolucency, internal/external root resorption, furcal radiolucency * hemorrhage at the site of amputation controlled with 5 minutes * tooth should be vital with healthy peridontium * tooth should be restoreable Exclusion Criteria: * teeth without permanent successor * teeth with history of irreversible pulpitis * post amputation unsuccessful hemorrhage control even after 5 minutes * radiographic evidence of internal/external root resorption, furcal/periapical pathology * patients with drug allergies or systemic diseases * clinical signs of spontaneous pain, sinus tract, tenderness to percussion, pathological mobility
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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