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Ancient chinese music tunes tested as depression treatment

NCT ID NCT07653113

Symptom relief Sponsor: University of Malaya Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a unique music therapy, based on Traditional Chinese Medicine's five-element theory, can help men with depression and anxiety when added to their usual medication. One hundred male inpatients will receive either standard drugs alone, drugs plus regular music, or drugs plus this special resonance-based music therapy for four weeks. Researchers will measure changes in mood, anxiety, and physical markers like stress hormones and brain activity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Resonance-Based Chinese Five-Element Music Intervention (RFEMI)
What this could lead to
If effective, this music therapy could offer a drug-free way to boost mood and reduce anxiety for men hospitalized with depression.
What could go wrong
This is a small, early-stage trial with only 100 male participants, so results may not apply to everyone. The music therapy is added to standard care, so its standalone effect is unclear.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 44 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * meeting both the ICD-11 diagnostic criteria for depressive episode or recurrent depressive disorder and the TCM diagnostic criteria for Yu disease * diagnosis confirmed by two senior clinical physicians * planned inpatient stay longer than six weeks * no antidepressant medication in the previous six months and no music therapy in the previous year * male sex, age 18-44 years, junior secondary education or above, clear consciousness, and ability to communicate effectively * no other major physical disease or mental disorder * voluntary written informed consent and complete clinical records. Exclusion Criteria: * depression due to organic mental disorder, psychoactive substance use, or non-addictive substance use * serious organic disease or unstable vital signs * suicidal or violent tendency, or refusal to cooperate with treatment * hearing impairment * inability to follow the intervention protocol * incomplete scale data or clinical records.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety Depressive disorder Randomised controlled trial

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Datong Maternal and Child Health Hospital (formerly Datong First People's Hospital), Shanxi, China

    Shanxi, Shanxi, 037010, China

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