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Sing your way to better memory: music therapy trial for Alzheimer's shows promise

NCT ID NCT04666077

Symptom relief Sponsor: Icahn School of Medicine at Mount Sinai Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether daily singing of personally meaningful songs can boost memory and language in people with Alzheimer's disease or mild cognitive impairment. One hundred participants worked with a music therapist and sang a 'song of kin' at home for 12 months. Researchers measured changes in cognition, behavior, and daily living skills to see if this simple, enjoyable activity could make a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
music therapy singing intervention
What this could lead to
If it works, this could offer a simple, home-based activity to help maintain memory and language skills in people with Alzheimer's or mild cognitive impairment.
What could go wrong
This is a small, completed trial with 100 participants, so results may not apply to everyone. The intervention is behavioral, so benefits may be modest and not a substitute for medical treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Aug 2019

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of Alzheimer's disease or mild cognitive impairment * Must have study partner * English speaking * No verbal impairment * Community-dwelling * Must have webcam or smart phone Exclusion Criteria: * A diagnosis of dementia other than probable or possible AD * Probable AD with Down syndrome * History of a clinically significant stroke with residual deficit * Current evidence or history in past two years of epilepsy, focal brain lesion, head injury * Current diagnosis for major psychiatric disorder including psychosis, major depression, bipolar disorder, alcohol or substance abuse. * Participation in another interventional study * Comorbidity causing disability interfering with intervention such as pain or discomfort or life expectancy less than 1 year

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Caregiver Burden Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimer's disease Mild cognitive impairment

Contacts and locations

Locations

  • Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Louis Armstrong Center for Music and Medicine, Mount Sinai Beth Israel

    New York, New York, 10003, United States

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